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medical illustration of Scientists usually study cancer by looking at a single layer of cancer cells in a dish. But the reality of the tumour microenvironment is much more complex. New techniques are finally letting scientists study the complex ways in which different cell types communicate with one another inside the microenvironment.

Watch our full video on this complex cell signalling here: https://youtu.be/6Q4TuLXBEpg
medical illustration of This image, based on the results of the TracerX  lung cancer trial by Prof Charles Swanton at the Francis Crick Institute and UCL, was used as the cover of Nature, vol 545 issue 7655 May 25th 2017
medical illustration of Not only is oncogenic KRAS able to kickstart all kinds of proliferative signalling pathways inside a cell, it's able to hijack the behaviour of nearby fibroblasts as well. This causes the fibroblasts to release growth factors, which cause even more proliferative signalling in the cancer cells. 

See our full video here: https://youtu.be/GU-QZp5FwM8
medical illustration of See our full video on blood cancer here: https://youtu.be/B8nFk5j2hP4
medical illustration of By engineering a patient's own immune cells to be better at targeting cancer, doctors are now able to make truly personalised treatments.

You can find our full video on CAR-T cells here: https://youtu.be/w7mMamTRvko
medical illustration of Complex cell signalling between cancer cells, fibroblasts and immune cells.

This image was used on the cover of Trends in Biotechnology vol 34 no 8 August 2016
medical illustration of When cells inside a tumour die, they break up into little bits that can get into the bloodstream. That means that scientists can filter out traces of tumour DNA from the bloodstream and use it to track cancer.

Watch our full video on liquid biopsies here: https://youtu.be/ZJyvqhVWQyM
medical illustration of When cells inside a tumour die, they break up into little bits that can get into the bloodstream. That means that scientists can filter out traces of tumour DNA from the bloodstream and use it to track cancer.

Watch our full video on liquid biopsies here: https://youtu.be/ZJyvqhVWQyM
medical illustration of Find out more about tumour heterogeneity and we can target it with next generation immunotherapy here: https://youtu.be/ETSarsv9QhA
medical illustration of Find out more about tumour heterogeneity and we can target it with next generation immunotherapy here: https://youtu.be/ETSarsv9QhA
medical illustration of A pseudo-DUB, artwork we did to promote the 2018 EMBO conference on pseudoenzymes 

meetings.embo.org/event/18-pseudoenzymes
medical illustration of RNAse L, artwork we did to promote the 2018 EMBO conference on pseudoenzymes 

meetings.embo.org/event/18-pseudoenzymes
medical illustration of To watch our 3-part series on therapeutic antibodies, for University College London:

Part 1, antibody structure/function: https://youtu.be/ptnjKYEEheo
Part 2, therapeutic antibodies: https://youtu.be/Rsv_Swx3tSA
Part 3, antibody-drug conjugates: https://youtu.be/QDXcsSF3yl0
medical illustration of To watch our 3-part series on therapeutic antibodies, for University College London:

Part 1, antibody structure/function: https://youtu.be/ptnjKYEEheo
Part 2, therapeutic antibodies: https://youtu.be/Rsv_Swx3tSA
Part 3, antibody-drug conjugates: https://youtu.be/QDXcsSF3yl0
medical illustration of This still is from a video we did based on Prof. David Nutt's work at Imperial College London, investigating the use of psychedelic drugs in the treatment of depression:

https://youtu.be/ltqjHHZr-yM
medical illustration of Find out more about how kinases transmit signals in our breakdown video here: https://youtu.be/xG2WOd_fWqo
medical illustration of Find out more about how kinases transmit signals in our breakdown video here: https://youtu.be/xG2WOd_fWqo
medical illustration of Watch our video on how the proteosome works here: https://youtu.be/TgOe7aPVpoM
medical illustration of An accurate human shoulder: geometry isolated from an original MRI dataset, with added texturing.

Profile

At Phospho, we make your science stunning. We're a small team based in London, UK. We specialise in molecular, cellular, (immuno-)oncology, diagnostics and medical imaging visualisations, for charity, academia and industry partners. We're passionate about three things: making gorgeous imagery, telling engaging stories, and delivering the highest scientific accuracy. Most of our team have biochemistry PhDs, so we know how important it is to get the science absolutely spot on. We've posted some recent highlights here, but you can find much more on our website or youtube page (youtube.com/phosphouk). If you have any questions or would like to discuss ideas for a project, don't be shy: drop us an email or get in touch via phospho.co.uk.

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