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Edmond Alexander

Represented by

Shannon Associates
333 West 57th Street, Suite 809
New York, NY 10019
United States

medical illustration of Thrombopoietin (TPO) is a protein produced primarily in the liver that controls how many platelets are made. In people with chronic Idiopathic Thrombocytopenia (ITP) there usually isn't enough TPO (orange) reaching the bone marrow when platelet levels get low. TPO Receptor Agonist (green) works by stimulating megakaryocytes and their precursors in the bone marrow, leading to proliferation and differentiation of these cells.
medical illustration of A bispecific monoclonal antibody is engineered to simultaneously bind to a cytotoxic cell and a targeted tumor cell.
medical illustration of Unique cell proteins are distributed across the cell surface to accept communication signals from extracellular signaling ligands like hormones, neurotransmitters, cell recognition molecules and growth factors.
medical illustration of Protein-ligand binding activates the lipid membrane surface protein to trigger intracellular signaling pathways. CD38 is a surface protein for cell activation found on immune cells, and its deficiency is linked to impaired immune responses and metabolic disturbances.
medical illustration of Receptor Tyrosine Kinase (RTKs) are high-affinity cell surface receptors for cell maintenance but also initiate the development of many cancers. RTK occurs when a ligand attaches to the HER 2 receptor and then connects to the HER 3 receptor, signaling intracellular proteins to initiate cell division. Here, the ligand attaches to the HER 3 receptor but the anti-tumor drug (sphere at base of the receptor) prevents the joining of HER 3 and HER 2, resulting in membrane destruction and cell death.
medical illustration of The immune system is the human body’s amazing self defense system which fights off foreign invaders that threaten the health of the human body. Cancer is a formidable invader and an aggressive challenger. It can capture the human circulatory system to feed its survival and to transport its invasion to other areas of the body. It never plays by the rules. Your move.
medical illustration of Concept art for proposed gaming project depicting cyberoid brain.
medical illustration of Anticancer drug passes through the folate carrier of the tumor cells and prevents actions that promote cell division and angiogenesis.
medical illustration of Wall mural and branding image for a rheumatologist’s private practice who wished to convey that rheumatology is not only about joints and the skeleton but also a specialty that deals with autoimmune diseases, systemic inflammatory conditions and the immune system for a holistic diagnostic approach to restore health.
medical illustration of Antitumor drugs target the intracellular component of the signaling protein receptors VEGF and MET to block tumor angiogenesis and metastasis.
medical illustration of Myelin is the electrically-insulating phospholipid sheath that surrounds the axons of many neurons and enables impulses to hop or “propagate by saltation.”
medical illustration of Myelin is the electrically-insulating phospholipid sheath that surrounds the axons of many neurons and enables impulses to hop or “propagate by saltation.”
medical illustration of Platelets are small, irregularly-shaped anuclear cells circulating in the blood to maintain hemostasis by forming blood clots when damage to the endothelium of blood vessels occurs.
medical illustration of Blood loss stimulates fibrinogen to convert fibrin strands which then trap platelets and blood cells, forming a mesh that creates a hemostatic plug over the wound site.
medical illustration of Exogenous migratory therapy techniques use stem cells to repair damaged neurons after traumatic injury or degenerative disease.
medical illustration of Multiple sclerosis (MS) is a demyelinating disease that damages the insulating membranes of nerve cells and disrupts the ability of parts of the nervous system to communicate.
medical illustration of The human cell contains numerous organelles that govern cell function, survival and reproduction.
medical illustration of Concept art for proposed interactive game depicting how man will be miniaturized and be placed into a bio-engineered “ribosome-like” vessel capable of exploring the inside of human cells. Interactive gamers explore the intracellular environment to detect the future DNA health of individual cell groups as well as diagnose and treat disease.
medical illustration of Concept art for proposed interactive game depicting how man will be miniaturized and be placed into a bio-engineered “ribosome-like” vessel capable of exploring the inside of human cells. Interactive gamers explore the intracellular environment to detect the future DNA health of individual cell groups as well as diagnose and treat disease.
medical illustration of Concept art for an interactive gaming where players explore the human body at the cellular level. The spherized DNA molecule allows players to monitor the health of the cells being investigated.
medical illustration of Surface and ribbon representations of the Botulinum toxin protein produced by produced by the bacterium Clostridium botulinum.
medical illustration of Macrophages present antigens of destroyed pathogens on their surfaces for T cells to retrieve and thereby initiate the immune response.
medical illustration of Cancer cells are abnormal cells that divide uncontrollably and destroy body tissue.
medical illustration of Before successful cell division can occur the genomic information stored in chromosomes must be replicated, and the duplicated genome separated cleanly between cells.
medical illustration of Unicellular organisms like bacteria grow to a fixed size and then reproduce through binary fission - a form of asexual reproduction.
medical illustration of White blood cells are diverse immune system cells that defend the body against both infectious disease and foreign materials.
medical illustration of Cytokines are signaling proteins and glycoproteins that are used extensively in cellular communication for both innate and adaptive immune responses.
medical illustration of Exogenous migratory therapy techniques use stem cells to repair damaged neurons after traumatic injury or degenerative disease. For Stanford Department of Neurosurgery, Stanford University School of Medicine.
medical illustration of Because a virus is unable to reproduce outside a host cell, blocking the cell’s replication pathway will also block replication of the virus.
medical illustration of Dry eye damages the three tear film layers (mucin, aqueous and lipid) of the normal ocular surface and causes hypertonic stress to the corneal epithelial cells.
medical illustration of Factor IX, or Christmas factor, is one of the serine proteases of the coagulation system. Deficiency of this protein causes Hemophilia B.
medical illustration of Concept art for proposed gaming project depicting cyberoid circulatory system.
medical illustration of The left coronary artery arises from the aorta above the left cusp of the aortic valve and feeds the left side of the heart.
medical illustration of Visualization of the anatomical relationship of the liver and kidneys to highlight a detoxification program.
medical illustration of DNA microarray technology analyzes reproducible and aligned array patterns to bring order to large amounts of gene data.
medical illustration of When activated, mast cells rapidly release histamine, heparin, and various hormonal mediators by degranulation to regulate allergy, anaphylaxis and wound healing.
medical illustration of When macrophages destroy pathogens they place antigens on their surfaces to stimulate the immune system. T Cells then pick up the antigens and orchestrate the immune response.
medical illustration of Transmission of the swine flu virus from pigs to humans is not common and does not always lead to human influenza, often resulting only in the production of antibodies in the blood.
medical illustration of Monoclonal antibodies are “magic bullets” bioengineered to target specific cancer cells with a toxin delivered by its agent of selectivity.
medical illustration of Because monoclonal antibodies are monospecific antibodies that are made of identical immune cells that are all clones of a unique parent cell, monoclonal antibodies have monovalent affinity and bind to the same epitope.
medical illustration of When a monoclonal antibody attaches to the surface of a targeted cell it is encapsulated and brought into the cell where it then initiates cell destruction.
medical illustration of Mapping of interventional pathways into the cell for antitumor therapy.
medical illustration of Numerous intracellular pathways of tumor cells are being explored as delivery routes for new drug therapies designed to interrupt tumor cell replication by preventing angiogenesis and cell division.
medical illustration of ADAMTS13 is an enzyme produced by the vascular endothelium that cleaves von Willebrand Factor, a protein that mediates platelet adhesion and aggregation at sites of vascular injury. Deficient levels of ADAMTS13 allows platelets to bind to uncleaved von Willebrand Factor multimers and leads to thrombotic microangiopathy.
medical illustration of Destruction of virulent microbe strains is hampered by the microbe’s protective outer membrane. Stronger antimicrobial drugs are able to penetrate and destroy the outer membrane and expose the more vulnerable inner membrane.
medical illustration of Concept art depicting quinolone antibiotic attack on difficult-to-destroy pathogens.
medical illustration of After an antibiotic penetrates the tough exterior shell of a microbial cyst, the antibiotic “smart bomb” targets the inner membrane. For Alcon.
medical illustration of Nelarabine MOA for treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. For GlaxoSmithKline.
medical illustration of Normal, hyperactive, suppressed and recovering nerves. For Giant Creative.
medical illustration of Pulmonary hypertension drug therapy regimes can have negative affects on hepatocytes in the liver due to the build-up of bile salts. For Volibris® for GlaxoSmithKline.

Profile

Edmond is a certified medical illustrator and a Fellow of the Association of Medical Illustrators. He received a Bachelor of Science, in Pre Biological Oceanography and Art at the University of Southern Mississippi 1967. Edmond began his career in medical illustration at the University of Texas Medical Schools in Galveston and then in Dallas where he created medical illustration for print and motion media. While in Dallas he also taught for seven years at the Graduate Program in Biomedical Illustration at the University of Texas Southwestern Medical School. He specializes in the 2D and 3D visualizations of cellular and molecular subjects, pathophysiology, and drug modes-of-actions for pharmaceutical companies, their agencies, and medical publishers. His illustration was heavily influenced by the beauty of the Disney films during his childhood years, and the art of Frank Armitage during his formative years in medical illustration. He is known for his rich sense of color and his uniquely memorable visual solutions to complex subjects. Edmond is the recipient of numerous national and international awards for his illustrations, his work in motion media and natural science photography including the Association of Medical Illustrators, Texas Scientific Communicators, Biological Photographic Association, Health Science Communication Association, New York International Film and Television Festival, Houston International Film Festival, SeaSpace International Underwater Photography Exhibition, and Fort Worth and Austin Addy Awards. Edmond’s work was selected to exhibit in the juried Art of Medicine Exhibition, New York; featured in The Best in Medical Advertising, Rockport Publishers; featured in The Guild Handbook of Scientific Illustration, Van Nostrand Reinhold; and showcased in Kai’s Power Tools and Studio Secrets, IDG Books Worldwide.

Style/Techniques

Airbrush, Color, 3D

Subject/Specialties

Allergy / Immunology, Anatomy, Biotechnology, Cardiac Surgery / Cardiology, Cell biology / Histology, Disease Management, Gastroenterology, Genetics, Molecular Biology, Neuroscience, Neurosurgery, Ophthalmology, Pharmacology, Respiratory, Virology, Oncology, Mechanism of Action (MOA), Hemophilia