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Glutamate Receptor Gating Cycle 

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Improving Resolution by Cryo-EM: ß-galactosidase

medical illustration of This illustration highlights 3 cryo-electron microscopy (cryo-EM) structures of a gated ion channel in the brain in 3 conformations (left - resting, middle - active, right - desensitized).

Ionotropic glutamate receptors (iGluRs) mediate intercellular signaling in the nervous system. Their pore domain crosses the neuron's cell membrane, and when activated, they allow ions to flow across the membrane.
Next medical illustration of Molecular structure of the Zika virus, similar to Dengue virus.

Zika Virus Structure

This illustration highlights 3 cryo-electron microscopy (cryo-EM) structures of a gated ion channel in the brain in 3 conformations (left - resting, middle - active, right - desensitized). Ionotropic glutamate receptors (iGluRs) mediate intercellular signaling in the nervous system. Their pore domain crosses the neuron's cell membrane, and when activated, they allow ions to flow across the membrane.

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