SerbinCommunications

(805) 963-0439 | Toll-Free (800) 876-6425

www.serbin.com LA / NY / UK

Falconieri Visuals

Human P-glycoprotein (PGP) Catalytic Cycle 

Prev Next
Previous

Membrane Protein Preparation Methods for CryoEM

medical illustration of Schematic diagram of the catalytic cycle of multidrug transporter P-glycoprotein (P-gp, ABCB1). PGP hydrolyzes ATP in order to remove various drugs from the cell, and plays a role in drug resistance. 

This diagram summarizes findings from multiple cryo-electron microscopy (cryo-EM) structures.
Next medical illustration of This illustration summarizes 3 states of a gated ion channel in the brain (left - resting, middle - active, right - desensitized).

Ionotropic glutamate receptors (iGluRs) mediate intercellular signaling in the nervous system. Their pore domain crosses the neuron's cell membrane, and when activated, they allow ions to flow across the membrane.

Schematic diagram of the catalytic cycle of multidrug transporter P-glycoprotein (P-gp, ABCB1). PGP hydrolyzes ATP in order to remove various drugs from the cell, and plays a role in drug resistance. This diagram summarizes findings from multiple cryo-electron microscopy (cryo-EM) structures.

Keywords: Cartoon, Information Graphics, Education, Publishing, Biology, Cell biology / Histology, Disease Management, Molecular Biology, Pharmacology, Mechanism of Action (MOA)