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Ras and PI3K Pathways in Cancer 

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Graphical Abstract for CRISPR Complex Publication

medical illustration of  Ras and PI3K (p85/p110) are two signaling pathways downstream of growth factor receptors that promote enhanced cell survival in cancer cells.  The molecules in these pathways are depicted using structures of human proteins from the PDB where available. Proteins with little or no structural data of the human protein are depicted as circles proportional to their molecular weight.
Next medical illustration of Two approaches to membrane protein preparation for cryo-electron microscopy (cryoEM) shown in schematic diagram format, including the GraDeR technique for excess detergent removal and nanodiscs.

Membrane Protein Preparation Methods for CryoEM

Ras and PI3K (p85/p110) are two signaling pathways downstream of growth factor receptors that promote enhanced cell survival in cancer cells. The molecules in these pathways are depicted using structures of human proteins from the PDB where available. Proteins with little or no structural data of the human protein are depicted as circles proportional to their molecular weight.

Keywords: Education, Publishing, Professional Education, Research, Biology, Cell biology / Histology, Molecular Biology, Oncology, Mechanism of Action (MOA), Pathology

© Veronica Falconieri