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Coronavirus Entry 

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Hemisected Brain Model with Blood Supply

medical illustration of This piece depicts the mechanism of entry of coronavirus into host cells. The ribosome binding domain on S1 of the Spike protein binds ACE2. TMPRSS2 cleaves S1, exposing S2 of the Spike protein. S2 unfolds, inserts into the host cell membrane, and refolds. Refolding pulls the viral membrane and host membrane together to fuse. Viral RNA enters the host cell.
Next medical illustration of Left image depicts the anatomy of the habenula in an axial section of the brain. 

Right image depicts the efferent and afferent projections and the nuclei involved.

Habenula Anatomy & Efferent & Afferent Projections

This piece depicts the mechanism of entry of coronavirus into host cells. The ribosome binding domain on S1 of the Spike protein binds ACE2. TMPRSS2 cleaves S1, exposing S2 of the Spike protein. S2 unfolds, inserts into the host cell membrane, and refolds. Refolding pulls the viral membrane and host membrane together to fuse. Viral RNA enters the host cell.

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