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Kryski Biomedia

Kryski Biomedia

Mechanism of Action of TA-46 in Achondroplasia

CLN2 Mechanism of Disease

medical illustration of This molecular biology illustration shows a three-way comparison of the FGFR3 signalling pathway that regulates bone growth in normal, achondroplasia, and achondroplasia treated with TA-46. TA-46 is an investigational, soluble recombinant FGFR3 decoy in clinical trials by Therachon / Pfizer.

medical illustration of This mechanism of action illustration shows the signalling pathways of sFGFR3 impacting healthy bone growth, and how CNP partially imacts the FGFR3 pathway for chondrocyte proliferation and differentiation in the treatment of achondroplasia.

CNP Mechanism of Action

This molecular biology illustration shows a three-way comparison of the FGFR3 signalling pathway that regulates bone growth in normal, achondroplasia, and achondroplasia treated with TA-46. TA-46 is an investigational, soluble recombinant FGFR3 decoy in clinical trials by Therachon / Pfizer.

Keywords: Color, Information Graphics, Line with Color, Advertising / Marketing, Education, Technology, Research, Cell biology / Histology, Molecular Biology, Mechanism of Action (MOA)

© Diana Kryski