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Activated Platelets in aHUS 

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Hepatocyte Stress

medical illustration of Atypical Hemolytic Uremic Syndrome (aHUS) manifests by chronic uncontrolled complement activation leading to the continuous activation of platelets and endothelial cells. The resulting thrombi cause thrombotic microangiopathy which may result in sudden fatal thrombotic complications or in the progressive failure of vital organs, including the kidney, heart, and brain. For Alexion Pharmaceuticals.
Next medical illustration of Disease caused by decreased platelet production can be augmented by platelet-stimulating agents that interact with the transmembrane domains of the thrombopoietin receptors, thereby complementing native thrombopoietin that binds with the extracellular domains.

Platelet Stimulating Agent

Atypical Hemolytic Uremic Syndrome (aHUS) manifests by chronic uncontrolled complement activation leading to the continuous activation of platelets and endothelial cells. The resulting thrombi cause thrombotic microangiopathy which may result in sudden fatal thrombotic complications or in the progressive failure of vital organs, including the kidney, heart, and brain. For Alexion Pharmaceuticals.

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© Cynthia Turner