Receptor Tyrosine Kinase (RTKs) are high-affinity cell surface receptors for cell maintenance but also initiate the development of many cancers. RTK occurs when a ligand attaches to the HER 2 receptor and then connects to the HER 3 receptor, signaling intracellular proteins to initiate cell division. Here, the ligand attaches to the HER 3 receptor but the anti-tumor drug (sphere at base of the receptor) prevents the joining of HER 3 and HER 2, resulting in membrane destruction and cell death.
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© Edmond Alexander