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DNA Illustrations, Inc.

DNA Illustrations, Inc.

Inhibition of PI3K Pathway

IV Treatment

medical illustration of Mechanism of action of Duvelisib (Copiktra); oral delta and gamma PI3K inhibitor. This dual isoform blockage inhibits cell signaling within malignant B cells and between malignant cells and the tumor microenvironment (TME). Blocking PI3K delta pathways from activated BCR, cytokine, and CD40 receptors affects the growth and survival of malignant B cells.

medical illustration of Deleterious mutations in the BCRA1 and BCRA2 genes are the most common cause of hereditary breast and ovarian cancer. Illustration shows dramatization of extraction of DNA from a blood test. Chromosomes 17 and 13 show the location of BCRA mutations leading to double DNA breaks.

BCRA1 BCRA2 Genetic Testing

Mechanism of action of Duvelisib (Copiktra); oral delta and gamma PI3K inhibitor. This dual isoform blockage inhibits cell signaling within malignant B cells and between malignant cells and the tumor microenvironment (TME). Blocking PI3K delta pathways from activated BCR, cytokine, and CD40 receptors affects the growth and survival of malignant B cells.

Keywords: Color, Editorial, Cell biology / Histology, Oncology, Mechanism of Action (MOA)

© DNA Illustrations