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AML Treatment with Glasdegib 

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medical illustration of Glasdegib is a Hedgehog signaling pathway inhibitor used to treat chemotherapy resistant AML (acute myeloid leukemia). Glasdegib molecule attaches to the Smoothened transmembrane protein and inactivates the Hedgehog signaling pathway. Glasdegib sensitives cells and reduces chemotherapy resistance.
Next medical illustration of Cross section of the oropharynx of a sleeping woman exhibiting obstructive sleep apnea (OSA). OSA involves repetitive partial or complete pharyngeal collapse while sleeping resulting in either apnea or hypopnea. In the section we can see the soft palette and the posterior portion of the tongue occluding the airway (indicated with blue).

Obstructive Sleep Apnea

Glasdegib is a Hedgehog signaling pathway inhibitor used to treat chemotherapy resistant AML (acute myeloid leukemia). Glasdegib molecule attaches to the Smoothened transmembrane protein and inactivates the Hedgehog signaling pathway. Glasdegib sensitives cells and reduces chemotherapy resistance.

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