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Loss of Tumor Supressor Gene 

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Loss of Ras gene and Apoptosis

medical illustration of Colon cancer stage: Loss of tumor suppressor gene and cell progression outside basal membrane.
Next medical illustration of Colon cancer stage: Loss of p53 gene, increased cellular abnormalities and decreased cellular adhesion.

Colon cancer stage: Loss of tumor suppressor gene and cell progression outside basal membrane.

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