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Ubiquitination and TAP1 Trafficking 

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Ubiquitination and CFTR Trafficking

medical illustration of Illustrates the ubiquitination/deubiquitination of TAP1, which is integral to the presentation of a viral peptide to an MHC Class 1 molecule in the endoplasmic reticulum, so that the antigen can be expressed on the cell membrane. Pseudomonas eruginosa infection releases Cif into the cell, inhibiting TAP1 deubiquitination which is increasingly degraded, interfering with antigen presentation.
Next medical illustration of Plate designed for magazine advertising and brochure use to illustrate process of dental veneering, in which the enamel is partially removed and replaced by custom porcelain veneers.

Dental Veneering Procedure

Illustrates the ubiquitination/deubiquitination of TAP1, which is integral to the presentation of a viral peptide to an MHC Class 1 molecule in the endoplasmic reticulum, so that the antigen can be expressed on the cell membrane. Pseudomonas eruginosa infection releases Cif into the cell, inhibiting TAP1 deubiquitination which is increasingly degraded, interfering with antigen presentation.

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© William Scavone