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Diabetic Glomerulus 

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Bone Marrow

medical illustration of The diabetic glomerulus exhibits glomerular hypertrophy and mesangial matrix expansion due to the increase of intra- and extracellular proteins from advanced glycation end-products, increased basement membrane thickness, and podocyte apoptosis.
Next medical illustration of COX-2 selective NSAIDs were developed to maintain analgesia efficacy while minimizing the side effects associated with COX-1 inhibition. The cyclooxygenase enzyme is anchored to the endoplasmic reticulum membrane. Above it, released prostaglandin hormones soar into the cell. The COX-2 selective NSAID is blocked from the channel of access for COX-1, but gains entry at COX-2 site, and thereby inhibits the active site for pain prostaglandin creation.

Cyclooxygenases and NSAIDS

The diabetic glomerulus exhibits glomerular hypertrophy and mesangial matrix expansion due to the increase of intra- and extracellular proteins from advanced glycation end-products, increased basement membrane thickness, and podocyte apoptosis.

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© Cynthia Turner