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Tim Fitzgerald

Memory Depotentiation at the Synapse 

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medical illustration of This image generalizes the electrochemical steps involved in memory depotentiation at the synapse between neurons. A stimulus activates NMDAR, which then permit calcium entry into the cell. As the cell depolarizes, VGCC activates and allows more calcium to flow into the cell. This intracellular calcium-oscillation mobilizes proteins that will eventually cause the cell to degrade the AMPA receptors by means of endocytosis.
Next medical illustration of This illustration was part of a proposal for a pharmaceutical company’s presentation. The illustration shows molecules in the extracellular space hovering over proteins that are embedded in a lipid bilayer. There are visuals underneath the proteins to symbolize the actions that occur downstream when the molecules bind to their receptors.

Molecular illustration for Pharma. presentation

This image generalizes the electrochemical steps involved in memory depotentiation at the synapse between neurons. A stimulus activates NMDAR, which then permit calcium entry into the cell. As the cell depolarizes, VGCC activates and allows more calcium to flow into the cell. This intracellular calcium-oscillation mobilizes proteins that will eventually cause the cell to degrade the AMPA receptors by means of endocytosis.

Keywords: Color, Information Graphics, Education, Publishing, Research, Biology, Cell biology / Histology, Molecular Biology, Neuroscience, Pathology

© Tim Fitzgerald