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The Role of the Proteasome in Multiple Myeloma 

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AXS Studio Scientific Animation Show Reel 2018

Next medical illustration of Created for disease state education on the molecular pathways underlying osteoporosis. Sclerostin is one of many factors that affects the downregulation of osteoblasts and overactivity of osteoclasts. The resulting imbalance can lead to fragility fractures in patients with osteoporosis.

Osteoporosis Mechanism of Disease Animation

Our challenge for this oncology animation was to present the proteasome as both a vital tool for healthy cells, and a key weapon of survival for cancer cells. We based the structure of our proteasome and its function on data from peer reviewed literature. A warm palette and bright lighting underscore the idea that the proteasome is not a sinister force, but rather an innocuous player in a noxious process.

Keywords: Animation, 3D, Anatomy, Cell biology / Histology, Molecular Biology, Pharmacology, Oncology, Mechanism of Action (MOA), Pathology

AXS Studio Inc.