This animation begins with the burden of disease of migraine, moves through pathophysiology, then dives into the story of a key molecular player: CGRP. We depict the localization of CGRP and its receptor in the CNS and peripheral structures and show receptor binding on a molecular level, within a synaptic cleft. A thorough review of the migraine literature informed the script and visuals.
Keywords: Animation, 3D, Anatomy, Molecular Biology, Neuroscience, Pharmacology, Mechanism of Action (MOA)
AXS Studio Inc.