Keri Leigh Biomedical Creations LLC

Coronavirus Entry 

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Slipped Capital Femoral Epiphysis

medical illustration of This piece depicts the mechanism of entry of coronavirus into host cells. The ribosome binding domain on S1 of the Spike protein binds ACE2. TMPRSS2 cleaves S1, exposing S2 of the Spike protein. S2 unfolds, inserts into the host cell membrane, and refolds. Refolding pulls the viral membrane and host membrane together to fuse. Viral RNA enters the host cell.
Next medical animation of Animation depicts neutrophil rolling and leaving blood vessel (extravasation) in response to infection.

Leukocyte in Blood Vessel

This piece depicts the mechanism of entry of coronavirus into host cells. The ribosome binding domain on S1 of the Spike protein binds ACE2. TMPRSS2 cleaves S1, exposing S2 of the Spike protein. S2 unfolds, inserts into the host cell membrane, and refolds. Refolding pulls the viral membrane and host membrane together to fuse. Viral RNA enters the host cell.

Keywords: Color, Line with Color, Education, Web, Research, Allergy / Immunology, Disease Management, Molecular Biology, Virology, Mechanism of Action (MOA)