XVIVO

medical animation of CRISPR gene editing is groundbreaking but complex. For Intellia Therapeutics, we created a patient-friendly animated experience to help clinical trial participants understand how CRISPR works- clearly, accurately, and with a sense of warmth and curiosity.
medical animation of We partnered with Reselute to build a 3D Medical device animation around their Reselution™ Intramedullary Fixation System, focusing on what makes it different and why it matters in the context of high-risk fractures. The piece takes the audience from the clinical problem into the surgical workflow, showing how the device is prepared and used in the operating room.
medical animation of We partnered with Cleveland Diagnostics to develop a 1:20-minute medical animation introducing IsoPSA, a next-generation blood test designed to improve prostate cancer risk assessment. Our challenge was to show how IsoPSA moves beyond traditional PSA testing in a way physicians and patients could immediately understand.
medical animation of For the launch of their booth at ISCT 2025 in New Orleans, and the debut of their new website, VitaCyte partnered with XVIVO to create a two-minute medical animation that details the science of cell recovery. Working with the VitaCyte team is always a highlight for us, and this project was a perfect mix of collaboration and science communication.
medical animation of Celldex returned to XVIVO to create a medical animation explaining the mechanism behind barzolvolimab, a monoclonal antibody that targets mast cells. After first working together in 2011, collaborating again with Celldex founder and CSO, Dr. Tibor Keler, made this project both meaningful and a reminder of why we love telling science stories.
medical animation of Biohaven Pharmaceuticals and XVIVO teamed up again, this time to create a mechanism of action animation for BHV-7000, their recently-acquired Kv7 activator. The BHV-7000 molecule blocks the action of the voltage-gated Kv7 potassium ion channel, which exquisitely regulates the excitability of neurons in the central nervous system.
medical animation of Sickle cell disease is an inherited genetic disease that has serious impacts on the people living with it. Forma Therapeutics is fiercely dedicated to improving the lives of these patients. XVIVO and Forma partnered together for multiple medical animation projects to educate both healthcare professionals and patients on their scientific approach.
medical animation of Moderna was creating a curriculum to inspire and educate learners about the opportunity mRNA presents as a medicine. The objective was to create an engaging online lecture that would serve both internal company training and public education. For XVIVO, it involved producing over 30 minutes of high-quality 3D animation focusing on mRNA technology, molecular and cellular processes, and therapeutic advancements.
medical animation of XVIVO and Korro Bio continued their partnership to create an animation for Korro’s RNA editing oligonucleotide candidate for alpha-1 antitrypsin deficiency (AATD) from their proprietary OPERA™ platform. The purpose of the animation was to illustrate the unmet need for AATD patients, the role of the protein AAT in the disease, and the promise of Korro’s RNA editing candidate.
medical animation of We collaborated with Max Hodak, the CEO of Science Corporation, to create a 3D animation to accurately and beautifully depict their breakthrough biohybrid technology. The animation showcases the architecture of their system and illustrates how their innovative technology facilitates communication to and from the brain.
medical animation of We partnered with ENT1DEP to animate this hypothesis. The animation follows the virus from entry through the respiratory or gastrointestinal tract, into the bloodstream, and into the beta cells themselves. From there, we take the viewer inside the cell, showing how a persistent low-grade infection may stress beta cells over time, overwhelm their machinery, and ultimately trigger an autoimmune response that destroys them.
medical animation of Working closely with the Hemanext team, we crafted medical animations to elucidate the science behind oxidative damage in stored blood. To leverage the visuals for multiple communication needs, the content was broken into chapters. The version we show here outlines the molecular components of blood involved in oxygen delivery, how storage can affect them, and the subsequent impacts on transfusion.
medical animation of XVIVO partnered with Lexicon Pharmaceuticals to create a series of high end medical animations that provide an overview of carcinoid syndrome diarrhea (CSD). The program illustrates how XERMELO, through the inhibition of TPH, turns down the overproduction of serotonin within neuroendocrine tumor cells, helping patients gain control over carcinoid syndrome.
medical animation of With Alexion Pharmaceuticals, we created a Soliris mechanism of action animation for the treatment of Myasthenia Gravis (MG). MG is an autoimmune disorder characterized by neuromuscular transmission failure and subsequent voluntary muscle weakness.
medical animation of Biorez has pioneered the BioBrace, the first ‘biocomposite’ soft tissue scaffold engineered to both mechanically reinforce tendon and ligament repairs, and enhance healing through its unique material properties and open architecture.
medical animation of Ankyra Therapeutics teamed up with XVIVO on a scientific MOA animation touting their anchored immunotherapy approach to cancer treatment, which is designed to promote prolonged immune activation at the tumor site while limiting systemic toxicity that can be associated with other immunotherapy.
medical animation of The Inner Life of the Cell medical animation was created to help educate college students and, along the way, ended up giving XVIVO an orbital boost. Since its development in 2006, the animation has been used worldwide by educators, scientists, and news outlets to help explain the inner life of a cell and inspired other animators and researchers in their own works.
medical animation of XVIVO teamed up with Harvard to develop a 3D animation for their Molecular and Cellular Biology students about the microscopic world of mitochondria. This video highlights the creation of Adenosine Triphosphate (ATP) – mobile molecules that store chemical energy derived from the breakdown of carbon-based food.
medical animation of Harvard University and XVIVO come together again to add to the growing series of scientific animations for BioVisions – Harvard’s multimedia lab in the department of Molecular and Cellular Biology.
medical animation of XVIVO and DePuy Synthes (a Johnson & Johnson company) recently partnered on an animation of their CONDUIT™ Interbody medical devices to help healthcare providers understand the level of engineering and detail that is embedded in the devices, with the goal of optimizing efficacy. The animation is used as playback loop in a conference booth and as an asset for live presentations, with images from the animation used for print and digital enduring materials.
medical animation of As part of a patient education series for Cancer Treatment Centers of America, XVIVO created multiple animations to exist online alongside patient case studies and interviews. This particular animation was designed to be an approachable overview of clinical trials. The video discusses how clinical trials are conducted, the phases of the trials, and the goals of the study.
medical animation of The animation presents fine visual detail of the eye anatomy, including the sinuous path of the episcleral veins and the cross-sectional view of the retina that so closely resembles human anatomy, you would think you were examining someone’s actual eye. With this dynamic and detailed animation, healthcare providers, consumers, and investors can better understand how eye pressure is regulated and how Qlaris Bio is attempting to innovate in the field.
medical animation of The Vaccine Makers Project (VMP) is the classroom-based program of the Vaccine Education Center at Children’s Hospital of Philadelphia. As partners in this educational initiative, XVIVO has created a series of videos illustrating how the human immune system and vaccines work together to fight diseases.
medical animation of The most recent animation program we developed for Listerine detailed the MOA of Listerine and presented exciting new data on how Listerine reduced plaque buildup compared to flossing.
medical animation of Dr. Parth Shah, the Director of Vascular and Endovascular Surgery at the Thoracic Outlet Center at Hartford Healthcare’s Heart and Vascular institute asked XVIVO to create an animation of a surgery he performs to relieve a condition called thoracic outlet syndrome, or TOS. The animation contains very detailed visuals and voice over to inform patients and families about the procedure, and which could also serve as educational material on TOS surgery for surgeons-in-training.
medical animation of X4 Pharmaceuticals wanted to create a 3D medical animation for the launch of their therapeutic XOLREMDITM, indicated for the treatment of WHIM syndrome, a rare immunodeficiency disorder. The main goal was to communicate the complexity of WHIM syndrome and how XOLREMDI cuts through this complexity by targeting the underlying cause of the disease.

Profile

XVIVO Scientific Animation is an award-winning medical animation studio with over 25 years of experience translating complex science into clear, compelling, and memorable visuals. Based in Wethersfield, Connecticut, XVIVO serves a wide range of clients across the life sciences, from global pharmaceutical leaders like Johnson & Johnson, Pfizer, Moderna, and Ipsen, to pioneering biotech companies, medical device innovators, and early-stage startups. Academic and government partners have included Harvard University, St. Jude Children's Research Hospital, the Children's Hospital of Philadelphia (CHOP), and the National Institutes of Health. XVIVO's team of Certified Medical Illustrators, PhD script writers, and seasoned 3D artists brings deep scientific expertise and visual thinking to every project. Their services span 3D and 2D animation, medical illustration, interactive touch screen experiences, as well as virtual and augmented reality. The studio is perhaps best known for creating The Inner Life of the Cell, a landmark animation developed in partnership with Harvard University that became a defining moment in the field of scientific visualization. XVIVO's work has been featured in The New York Times, shown at TED and TEDMED, exhibited at the Museum of Modern Art, and presented at the World Science Festival and the World Economic Forum, bringing cutting-edge science to various audiences across the globe. With an average staff tenure of over ten years and hundreds of successful programs completed, XVIVO brings a rare combination of scientific credibility, creative excellence, and a truly collaborative spirit to every project. Underlying all of it is a deeply held belief that science needs to be understood, not just by specialists, but by patients, caregivers, investors, and the broader public. Because when people understand their own biology, how diseases can unfold, and what science makes possible, lives improve.

Style/Techniques

Animation, Cartoon, Information Graphics, 3D, Video, Voiceovers/Narration

Subject/Specialties

Allergy / Immunology, Anatomy, Biology, Biotechnology, Cell biology / Histology, Dentistry, Disease Management, Endocrinology / Metabolic, General Medicine, General Surgery, Genetics, Medical Devices, Molecular Biology, Natural Science / Nature, Neuroscience, Neurosurgery, Ophthalmology, Orthopaedics, Reconstructive Surgery, Thoracic Surgery, Vascular Surgery, Virology, Injuries, Oncology, Mechanism of Action (MOA), Hemophilia, Sports Medicine