BrioTech

BrioTech-PMN-Trap

David Bolinsky

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Neutrophil extracellular trap, extracellular fibres composed of DNA from neutrophils which binds pathogens.

David Bolinsky

medical animation of A sampling of recent Emersionist Medical and Scientific Animations, demonstrating a range of styles reflecting differences budgets and audiences, but all with the highest attention to accuracy, memorability and aesthetics.
medical illustration of Navigable 3D model of neuron for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation. This model was also set up experimentally to be explored on an HTC Vibe VR system.
medical illustration of Bill Gates held a conference with Warren Buffet, of people working for and with the Bill and Melinda Gates Foundation. He singled out as a favorite, 'Inspark', the education grant project I spent two years on. It is a community college level interactive biology course based on 'Bio Beyond'.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This animation shows the layers of a blood vessel and tissues that naturally express the clot initiator, tissue factor. Circulatory system, lymphatic system, tunica intima, capillaries, aorta, arterial system
medical illustration of There are, according to research by Yale's Gordon Shepherd, an array of neurological pathways activated in sequence in order for the gustatory effects of food ingestion to be fully appreciated, as depicted in this animation.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the hearing module.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the hearing module.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the hearing module.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the hearing module.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation.Tissue Factor pathway Inhibitor is an early mechanism for limiting how much blood clotting progresses.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation.Tissue Factor pathway Inhibitor is an early mechanism for limiting how much blood clotting progresses.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This is from an interactive scene on platelet activation on a plasma membrane.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This is from an interactive scene on platelet activation on a plasma membrane.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the vision module.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the vision module.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the vision module.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the neuroplasticity module.
medical illustration of We created a series of sixteen animations for Oxford University Press to accompany a nursing neurophysiology book by David Eagleman. This is from the neuroplasticity module, showing a classic homunculus distribution of sensory information in the brain.
medical illustration of OncoSec has developed a method for directly stimulating T-cells to aggregate within a tumor, bypassing natural checkpoint inhibition that protects tumors from the immune system. This still from the animation shows a plasmid being introduced into the tumor environment where it will be adsorbed by various cells.
medical illustration of OncoSec has developed a method for directly stimulating T-cells to aggregate within a tumor, bypassing natural checkpoint inhibition that protects tumors from the immune system. This still from the animation shows an IL-12 coding plasmid having entered a tumor cell.
medical illustration of OncoSec has developed a method for directly stimulating T-cells to aggregate within a tumor, bypassing natural checkpoint inhibition that protects tumors from the immune system. This still from the animation shows a T-cell approaching a tumor cell that has had its checkpoint inhibition blocked.
medical illustration of OncoSec has developed a method for directly stimulating T-cells to aggregate within a tumor, bypassing natural checkpoint inhibition that protects tumors from the immune system. This still from the animation shows the IL-12 molecule coded by the plasmid.
medical illustration of OncoSec has developed a method for directly stimulating T-cells to aggregate within a tumor, bypassing natural checkpoint inhibition that protects tumors from the immune system. This still from the animation shows an antibody targeting the a T-cell attaching to a tumor cell that has had its checkpoint inhibition blocked.
medical illustration of OncoSec has developed a method for directly stimulating T-cells to aggregate within a tumor, bypassing natural checkpoint inhibition that protects tumors from the immune system. This still from the animation shows the T-cell inducing tumor cell apoptosis.
medical illustration of This three minute pilot animation was created for a production company in Mexico City to visualize a children's adventure book written by Julio Frenk, M.D. (now president of the University of Miami). The book follows the adventures thru the human body by three lively amino acid characters.
medical illustration of This three minute pilot animation was created for a production company in Mexico City to visualize a children's adventure book written by Julio Frenk, M.D. (now president of the University of Miami). The book follows the adventures thru the human body by three lively amino acid characters.
medical illustration of Animation, 3D, Models, Education, Multimedia, Publishing, Interactive, Anatomy, Gastroenterology, Health & Wellness
medical illustration of 3D animated zoom from the gross kidney, into the glomerulus.
medical illustration of 3D animated zoom from the gross kidney, into the glomerulus.
medical illustration of A zoom into the glomerulus.
medical illustration of 3D animated zoom from the gross kidney, into the glomerulus.
medical illustration of This three minute pilot animation was created for a production company in Mexico City to visualize a children's adventure book written by Julio Frenk, M.D. (now president of the University of Miami). The book follows the adventures thru the human body by three lively amino acid characters. This is part of the travels into the heart.
medical illustration of This three minute pilot animation was created for a production company in Mexico City to visualize a children's adventure book written by Julio Frenk, M.D. (now president of the University of Miami). The book follows the adventures thru the human body by three lively amino acid characters. here the characters approach the pituitary gland at the base of the brain.
medical illustration of This three minute pilot animation was created for a production company in Mexico City to visualize a children's adventure book written by Julio Frenk, M.D. (now president of the University of Miami). The book follows the adventures thru the human body by three lively amino acid characters. Here the characters are being transported in bubbles into a white blood cell perched on a neuron axon in the brain.
medical illustration of This three minute pilot animation was created for a production company in Mexico City to visualize a children's adventure book written by Julio Frenk, M.D. (now president of the University of Miami). The book follows the adventures thru the human body by three lively amino acid characters. Here the characters are being transported in bubbles into a white blood cell perched on a neuron axon in the brain.
medical illustration of From a series of web-based illustrations showing the biotechnology of AOBiome's live culture based skincare products.
medical illustration of From a series of web-based illustrations showing the biotechnology of AOBiome's live culture based skincare products. Color variation from previous image.
medical illustration of From a series of web-based illustrations showing the biotechnology of AOBiome's live culture based skincare products. This is a closeup in a skin pore in a discussion about transforming human health through the restoration of Ammonia-Oxidizing Bacteria, a natural component of the biome.
medical illustration of From a series of web-based illustrations showing the biotechnology of AOBiome's live culture based skincare products. This is a closeup of an Ammonia-Oxidizing Bacteria, a natural component of the biome.
medical illustration of One of a number of skin models developed to show the effects of sun, chemicals and aging on dermal and epidermal structures and the MOA of various cosmetic products on same.
medical illustration of From an interactive education project on coagulation of blood created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University), called Clot Quest, this is an image of encrypted tissue factor, an important link in post-platelet-activation clot formation.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This is from an animated interactive interface for navigation around the various proteins involved in coagulation.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This animation shows the activity around a vascular puncture that initiates platelet activation.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This animation shows the activity around a vascular puncture that initiates platelet activation.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This animation shows the activity around a vascular puncture that initiates platelet activation.
medical illustration of One of a series of interactive animations created in partnership with the Frank H. Netter School of Medicine (Quinnipiac University) for a project called Clot Quest - an interactive exploration of blood coagulation. This animation shows the consolidation of fibrin strands around a platelet plug..
medical illustration of Dr. Kadoch at the Dana Farber Clinic has been discovering complexes of proteins that are common to nearly all cancers and mediate DNA transcription in tumor cells, in what may be a huge breakthrough.
medical illustration of From a series of illustrations on CHF for an advertising/patient education piece.
medical illustration of For Unilever, this is from a series of animations showing the mechanism of action of bio-active cosmetic products in and on the skin.
medical illustration of For Unilever, this is from a series of animations showing the mechanism of action of bio-active cosmetic products in and on the skin.
medical illustration of For Unilever, this is from a series of animations showing the mechanism of action of bio-active cosmetic products in and on the skin. This animation showed the effects of photoaging on the skin.
medical illustration of One of several 3D models constructed for Unilever to show the skin damage from harsh chemicals and other external influences.
medical illustration of From an animation for an interactive community college science course on cell biology based on 'Bio Beyond', created with Smart Sparrow and Arizona State University for the Bill and Melinda Gates Foundation.
medical illustration of Estee Lauder is among many cosmetics companies developing bioactive cosmetics, using many naturally-occurring botanical ingredients. We explored the activity of five of those ingredients in this video. The stylistic intent was to bring an elegant look to the project while respecting the underlying science.
medical illustration of Estee Lauder is among many cosmetics companies developing bioactive cosmetics, using many naturally-occurring botanical ingredients. We explored the activity of five of those ingredients in this video. The stylistic intent was to bring an elegant look to the project while respecting the underlying science.
medical illustration of Estee Lauder is among many cosmetics companies developing bioactive cosmetics, using many naturally-occurring botanical ingredients. We explored the activity of five of those ingredients in this video. The stylistic intent was to bring an elegant look to the project while respecting the underlying science.
medical illustration of Estee Lauder is among many cosmetics companies developing bioactive cosmetics, using many naturally-occurring botanical ingredients. We explored the activity of five of those ingredients in this video. The stylistic intent was to bring an elegant look to the project while respecting the underlying science.
medical illustration of Estee Lauder is among many cosmetics companies developing bioactive cosmetics, using many naturally-occurring botanical ingredients. We explored the activity of five of those ingredients in this video. The stylistic intent was to bring an elegant look to the project while respecting the underlying science.
medical illustration of Estee Lauder is among many cosmetics companies developing bioactive cosmetics, using many naturally-occurring botanical ingredients. We explored the activity of five of those ingredients in this video. The stylistic intent was to bring an elegant look to the project while respecting the underlying science.
medical illustration of Navigable 3D model of a bacterial cell for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation.
medical illustration of Navigable 3D model of a bacterial cell for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation. This is a model of a bacterial cell wall.
medical illustration of Navigable 3D model of a plant cell for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation. This shows the tile-like approximation of plant cells.
medical illustration of Navigable 3D model of a plant cell for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation. This shows details of the plasmodesmata which allows communication and molecular movement between plant cells.
medical illustration of Navigable 3D model of a plant cell for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation. This shows details of the plasmodesmata which allows communication and molecular movement between plant cells.
medical illustration of Navigable 3D model of a plant cell for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation. This image shows details of the major cellular components of a plant cell.
medical illustration of Navigable 3D model of a plant cell for an interactive community college science course on cell biology, based on 'Bio Beyond', created with Smart Sparrow and Arizona State University from a grant from the Bill and Melinda Gates Foundation. This image shows details of a chloroplast of a plant cell.
medical illustration of This animation is a demonstration of changing scale on the fly into a liver cell from outside the body.
medical illustration of This animation is a demonstration of changing scale on the fly into a liver cell from outside the body.
medical illustration of This animation is a demonstration of changing scale on the fly into a liver cell from outside the body. Here we see the modular arrangement of hepatocytes in a liver lobule.
medical illustration of This animation is a demonstration of changing scale on the fly into a liver cell from outside the body. Here we see the modular arrangement of hepatocytes in a liver lobule and the central vein.
medical illustration of This animation is a demonstration of changing scale on the fly into a liver cell from outside the body. Here we see the modular arrangement of hepatocytes in a liver lobule. We see increased detail of individual hepatocytes as we approach.
medical illustration of Diving into the cytoplasm of the hepatocyte we see typical cellular organelles.
medical illustration of Diving into the cytoplasm of the hepatocyte we see typical cellular organelles.
medical illustration of Diving into the cytoplasm of the hepatocyte we see typical cellular organelles.
medical illustration of Diving into the cytoplasm of the hepatocyte we see typical cellular organelles.
medical illustration of Diving into the cytoplasm of the hepatocyte we see typical cellular organelles.
medical illustration of We create visually functional, accurate and aesthetically pleasing digital models of technology prototypes for marketing and virtual testing.
medical illustration of We create visually functional, accurate and aesthetically pleasing digital models of technology prototypes for marketing and virtual testing.
medical illustration of Anatomically accurate 3D reconstruction of a dendritic cell.
medical illustration of Nativis has developed a molecular biology approach to treating glioblastoma that avoids surgery, chemo and radiation. Our animation shows the technology breakthrough and the MOA. This image shows the tight juncture of the blood brain barrier that prevents effective chemotherapy of brain cancers.
medical illustration of Nativis has developed a molecular biology approach to treating glioblastoma that avoids surgery, chemo and radiation. Our animation shows the technology breakthrough and the MOA. This sequence shows the effect of checkpoint inhibition preventing an effective immune response to glioblastoma tumor cells.
medical illustration of Nativis has developed a molecular biology approach to treating glioblastoma that avoids surgery, chemo and radiation. Our animation shows the technology breakthrough and the MOA.This image tells the theory behind RNA interference technology.
medical illustration of Nativis has developed a molecular biology approach to treating glioblastoma that avoids surgery, chemo and radiation. Our animation shows the technology breakthrough and the MOA. With checkpoint inhibition turned off, T-cells aggressively attack glioblastoma cells in situ.
medical illustration of Nativis has developed a molecular biology approach to treating glioblastoma that avoids surgery, chemo and radiation. Our animation shows the technology breakthrough and the MOA. With checkpoint inhibition turned off, T-cells aggressively attack glioblastoma cells in situ.
medical illustration of Nativis has developed a molecular biology approach to treating glioblastoma that avoids surgery, chemo and radiation. Our animation shows the technology breakthrough and the MOA. With checkpoint inhibition turned off, T-cells aggressively attack glioblastoma cells in situ causing them to enter apoptosis.
medical illustration of This is one of 25 short animations created for a TED MED talk by Charity Sunshine Tillemann Dick about her second double lung transplant and how she regained her world-class skills as a coloratura soprano afterward.
medical illustration of Cystic fibrosis transmembrane conductance regulator (CFTR) can be genetically modified to remediate the worst aspects of the disease. This video discusses how the mechanism was modulated to good effect in several patients, for a professional conference at Johns Hopkins University.
medical illustration of Cystic fibrosis transmembrane conductance regulator (CFTR) can be genetically modified to remediate the worst aspects of the disease. This video discusses how the mechanism was modulated to good effect in several patients, for a professional conference at Johns Hopkins University.
medical illustration of Cystic fibrosis transmembrane conductance regulator (CFTR) can be genetically modified to remediate the worst aspects of the disease. This video discusses how the mechanism was modulated to good effect in several patients, for a professional conference at Johns Hopkins University.
medical illustration of Aperion has developed a methodology to remove antigens from pig tissues used to replace ligaments in orthopedic repairs of the ACL, to remove the post-surgical immune response.
medical illustration of Aperion has developed a methodology to remove antigens from pig tissues used to replace ligaments in orthopedic repairs of the ACL, to remove the post-surgical immune response.
medical illustration of Aperion has developed a methodology to remove antigens from pig tissues used to replace ligaments in orthopedic repairs of the ACL, to remove the post-surgical immune response.
medical illustration of This image was for possible use as a Science cover art by Harvard's David Sinclair. The research involved the discovery of a new protein domain that senses the small molecule NAD and controls DNA repair. Implications for humans are age-reversal and the protection of astronauts in deep space from gamma ray damage.
medical illustration of 3D model of Narcissus tazetta (Chinese sacred lily) and bulb. The bulb extract can reduce hyperpigmntation of the skin and is used in some cosmetics.
medical illustration of From a series of interactive animations for Unilever comparing normal skin structures and how differently they respond to chronological aging and photodamage.
medical illustration of From a series of interactive animations for Unilever comparing normal skin structures and how differently they respond to chronological aging and photodamage.
medical illustration of From a series of interactive animations for Unilever comparing normal skin structures and how differently they respond to chronological aging and photodamage.
medical illustration of From a series of interactive animations for Unilever comparing normal skin structures and how differently they respond to chronological aging and photodamage.
medical illustration of From a series of interactive animations for Unilever comparing normal skin structures and how differently they respond to chronological aging and photodamage. Dermatologist, sun damage, ultraviolet (UV) light, skin cancer

Profile

David is an accomplished and award-winning medical illustrator and animator whose ground-breaking career in digital animation spans 33 years. After holding the position of Senior Medical Illustrator at the Yale School of Medicine, David founded the world’s first digital medical animation company, Advanced Imaging, Inc., in 1984. In 2000, David co-founded XVIVO Scientific Animation. Major clients include global corporations such as Merck, Genentech, Novartis, and Pfizer, museums such as the Smithsonian and Chicago’s Museum of Science and Industry (on the Permanent Advisory Council); DARPA; universities such as Yale, Johns Hopkins, Harvard, Cambridge, UCSF, Chalmers, Texas A&M, U of Illinois, Chicago. David has spoken at numerous international and US conferences and universities, including TED India; AYACC in Guiyang, China; CUTEC-TVC Conference, Cambridge University, UK; University of Gothenburg, Sweden; Tokyo Design Gakuin College, Tokyo/Osaka/Nagoya/Fukuoka, Japan; Co-host, Global 3D Tech Forum, Gangnam, South Korea; Zurich Minds, Zurich, Switzerland; the FutureMed Lectures at Singularity University; the USA Science & Engineering Festival in Washington DC; the World Science Festival in New York and Humanity+ Conference at Harvard and UCSF. A two-time speaker at the TED Conference, in 2007 he presented the highly acclaimed animation “The Inner Life of a Cell”. David is a guest faculty member of Singularity University and affiliates, Future Medicine and the Exponential Medicine Conference, and an associate partner in the 'Marie Curie Initiative' with the University of Utrecht, Netherlands. More detailed bio available.

Style/Techniques

Animation, Design, Line with Color, 3D, Apps/Mobile, Models, Video, Microscopy, VR/Virtual Reality

Subject/Specialties

Allergy / Immunology, Alternative Medicine, Anatomy, Biology, Biotechnology, Botany, Cardiac Surgery / Cardiology, Cell biology / Histology, Dermatology, Disease Management, Emergency Medicine, Endocrinology / Metabolic, Gastroenterology, General Medicine, General Surgery, Medical Devices, Molecular Biology, Natural Science / Nature, Neuroscience, Ophthalmology, Orthopaedics, Physical Therapy, Reconstructive Surgery, Respiratory, Thoracic Surgery, Transplantation Surgery, Urology, Vascular Surgery, Injuries, Oncology, Mechanism of Action (MOA), Health & Wellness, Hemophilia, Pathology