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Cytochrome P450 3A4 

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Pfu-Pol on gold particle

medical illustration of Cytochrome P450 3A4 (CYP3A4) is an enzyme responsible for degrading many compounds (xenobiota). Grapefruit contains several chemicals, including bergamottin and nirangin visualised here, which bind and block the active site of CYP3A4. This can increase the level of therapeutics in patients and therefore cause severe side effects, possibly interferring with chemotherapeutics.
Next medical illustration of The most important concept in molecular biology is that DNA is made to RNA and RNA is made to protein. Until a few years ago regulation and appearance of the RNA polymerase was unclear, but with new methods structure could be decrypted and mechanisms clarified.

RNA Polymerase

Cytochrome P450 3A4 (CYP3A4) is an enzyme responsible for degrading many compounds (xenobiota). Grapefruit contains several chemicals, including bergamottin and nirangin visualised here, which bind and block the active site of CYP3A4. This can increase the level of therapeutics in patients and therefore cause severe side effects, possibly interferring with chemotherapeutics.

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