Cytochrome P450 3A4 (CYP3A4) is an enzyme responsible for degrading many compounds (xenobiota). Grapefruit contains several chemicals, including bergamottin and nirangin visualised here, which bind and block the active site of CYP3A4. This can increase the level of therapeutics in patients and therefore cause severe side effects, possibly interferring with chemotherapeutics.
Keywords: Color, 3D, Research, Biology, Biotechnology, Molecular Biology, Natural Science / Nature, Oncology, Health & Wellness, Pathology
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