Epigenetic mechanisms contribute to many diseases, as they contribute to the age-related erosion of gene expression program as well as the establishment of aberrant transcriptional programs in pathologies. Recent research has highlighted the roles of readers of the epigenetic code, which include PWWP1-domain containing proteins. The motif binds to Histone-4 methylated at lysine-20, H4K20me, suggesting it mediates some of the downstream functions of this critical epigenetic mark.
Keywords: Color, 3D, Research, Biotechnology, Genetics, Medical Devices, Molecular Biology, Natural Science / Nature, Pharmacology, Oncology
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