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Activated Platelets in aHUS 

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MOA- Blocking the Immune Checkpoint Inhibitor

medical illustration of Atypical Hemolytic Uremic Syndrome (aHUS) manifests by chronic uncontrolled complement activation leading to the continuous activation of platelets and endothelial cells. The resulting thrombi cause thrombotic microangiopathy which may result in sudden fatal thrombotic complications or in the progressive failure of vital organs, including the kidney, heart, and brain. For Alexion Pharmaceuticals.
Next medical illustration of The anatomical site of aqueous humour production in healthy ciliary processes epithelium and the aqueous humor drainage through healthy trabecular meshwork in the anterior chamber angle.

Aqueous Humor Production Anatomy

Atypical Hemolytic Uremic Syndrome (aHUS) manifests by chronic uncontrolled complement activation leading to the continuous activation of platelets and endothelial cells. The resulting thrombi cause thrombotic microangiopathy which may result in sudden fatal thrombotic complications or in the progressive failure of vital organs, including the kidney, heart, and brain. For Alexion Pharmaceuticals.

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