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MOA- Blocking the Immune Checkpoint Inhibitor 

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Bionic Stem Cell Portal

medical illustration of PD-1 & PD-2 (Programmed Death) protein receptors on tumor cells down regulates the immune system and promotes self-tolerance by suppressing TCell anti-inflammatory activity. When this protein is blocked, the “brakes” on the immune system are released and the ability of T Cells to kill cancer cells is increased.
Next medical illustration of Atypical Hemolytic Uremic Syndrome (aHUS) manifests by chronic uncontrolled complement activation leading to the continuous activation of platelets and endothelial cells. The resulting thrombi cause thrombotic microangiopathy which may result in sudden fatal thrombotic complications or in the progressive failure of vital organs, including the kidney, heart, and brain. For Alexion Pharmaceuticals.

Activated Platelets in aHUS

PD-1 & PD-2 (Programmed Death) protein receptors on tumor cells down regulates the immune system and promotes self-tolerance by suppressing TCell anti-inflammatory activity. When this protein is blocked, the “brakes” on the immune system are released and the ability of T Cells to kill cancer cells is increased.

Keywords: Color, 3D, Advertising / Marketing, Allergy / Immunology, Biology, Disease Management, Pharmacology, Oncology

© Cynthia Turner