Audra Geras

The Weber Group

Thrombus Formation 

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Nevo coronary Stent

medical illustration of This 3D illustration shows the early stages in the formation of a plaque-induced blood clot or thrombus. Damage to the endothelial cells lining the blood vessel lumen exposes a variety of platelet-activating factors, including collagen fibres, to the circulating blood. Platelets coming into contact with these factors adhere to the plaque surface and undergo dramatic morphologic changes. This is the first step in the initiation of a complex coagulation cascade leading to thrombus formation.
Next medical illustration of This 3D image was displayed in a pharmaceutical exhibit at a conference focused on lysosomal diseases. It features the molecule, alpha-galactosidase A, which is deficient in Fabry disease. Fabry disease is a rare genetic lysosomal storage disorder.

Fabry Disease

This 3D illustration shows the early stages in the formation of a plaque-induced blood clot or thrombus. Damage to the endothelial cells lining the blood vessel lumen exposes a variety of platelet-activating factors, including collagen fibres, to the circulating blood. Platelets coming into contact with these factors adhere to the plaque surface and undergo dramatic morphologic changes. This is the first step in the initiation of a complex coagulation cascade leading to thrombus formation.

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