Immune Response to Variant of VSG on Trypanosomes 

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Trypanosomiasis

medical illustration of This illustration shows a Trypanosome bruceii organism in the blood stream and the immune response to variant surface glycoproteins (VSGs) on the Trypanosome cell membrane. VSGs trigger an immune response via pentameric Immunoglobulin M antibodies. Trypanosome bruceii causes African sleeping sickness.
Next medical illustration of The illustration shows part 1 of the mode of action of SIRP-alpha Fc in triggering tumor cells to give off an 'eat me' signal to phagocytic macrophages. This painting is the first  half of a 120

SIRP-alpha Fc MOA - Part 1 of Diptych Mural

This illustration shows a Trypanosome bruceii organism in the blood stream and the immune response to variant surface glycoproteins (VSGs) on the Trypanosome cell membrane. VSGs trigger an immune response via pentameric Immunoglobulin M antibodies. Trypanosome bruceii causes African sleeping sickness.

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© Audra Geras