John Karapelou / Biomedical Art

Cannabinoid signaling at the synapse 

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Insulin binding to its receptor

medical illustration of Synthesis and expression of ligands specific to CB1 cannabinoid receptors on a presynaptic neuron at a synapse in the brain that regulate calcium ion flow, resulting in a reduction of glutamate neurotransmitter released.
Next medical illustration of CB2 is a cell receptor and part of the endocannabinoid system (ECS), and plays a critical role in immune system control, depicted here effecting an arteriole. Arterioles and their actively changing cellular functions during inflammation are associated with many inflammatory disorders.

CB2 Receptor Effects on Inflammation

Synthesis and expression of ligands specific to CB1 cannabinoid receptors on a presynaptic neuron at a synapse in the brain that regulate calcium ion flow, resulting in a reduction of glutamate neurotransmitter released.

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© John W. Karapelou