SerbinCreative

(805) 963-0439 | Toll-Free (800) 876-6425

www.serbincreative.com LA / NY / UK

DNA Illustrations, Inc.

Inhibition of PI3K Pathway 

Prev Next
Previous

IV Treatment

medical illustration of Mechanism of action of Duvelisib (Copiktra); oral delta and gamma PI3K inhibitor. This dual isoform blockage inhibits cell signaling within malignant B cells and between malignant cells and the tumor microenvironment (TME). Blocking PI3K delta pathways from activated BCR, cytokine, and CD40 receptors affects the growth and survival of malignant B cells.
Next medical illustration of Interpretation of Hemoglobin S polymerization. A genetic mutation causes the production of hemoglobin S (Hb S). When deoxygenated,  Hb S has the ability to polymerize into rigid rods which reshape the erythrocyte. The sickle shaped erythrocyte is much less flexible, which leads to hemolysis, increased viscosity and acute vaso-occlusive episodes.

Sickle Cell Anemia MOD

Mechanism of action of Duvelisib (Copiktra); oral delta and gamma PI3K inhibitor. This dual isoform blockage inhibits cell signaling within malignant B cells and between malignant cells and the tumor microenvironment (TME). Blocking PI3K delta pathways from activated BCR, cytokine, and CD40 receptors affects the growth and survival of malignant B cells.

Keywords: Color, Editorial, Cell biology / Histology, Oncology, Mechanism of Action (MOA)

© DNA Illustrations