PROTAC stands for proteolysis-targeting chimera. A PROTAC is composed of two or three molecules and is used to induce targeted proteolysis. The use of proteolysis-targeting chimeras (PROTACs) is a new technology utilizing a intracellular ubiquitin-proteasome for removal of unwanted proteins. It is valuable in cancer therapies. Bifunctional PROTAC molecule, covalently linked ligand of an E3 ubiquitin ligase (E3), ligand protein of interest (POI), targeted cancer therapy
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