Shown is the process of detecting fetal trisomy with the use of cell-free DNA (cfDNA) in maternal plasma.The fragments are sequenced and aligned to a reference set of chromosome sequences. A counting process is then used to determine the relative amount of cfDNA from each chromosome and to investigate whether any are overrepresented. Overrepresentation of sequences from chromosome 21 suggests that the fetus has trisomy 21. N Engl J Med 2022; 387:1322-1324 DOI: 10.1056/NEJMcibr2209405
Keywords: Color, Education, Professional Education, Anatomy, Biology, Genetics, Maternal / Child, Reproductive Biology, Health & Wellness
© MMS