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Use of Cell-free DNA in Maternal Plasma 

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Trypanosoma brucei

medical illustration of Shown is the process of detecting fetal trisomy with the use of cell-free DNA (cfDNA) in maternal plasma.The fragments are sequenced and aligned to a reference set of chromosome sequences. A counting process is then used to determine the relative amount of cfDNA from each chromosome and to investigate whether any are overrepresented. Overrepresentation of sequences from chromosome 21 suggests that the fetus has trisomy 21. N Engl J Med 2022; 387:1322-1324
DOI: 10.1056/NEJMcibr2209405
Next medical illustration of Images created for the AMA (Current Procedural Terminology) CPT Assistant Newsletter and the CPT Professional code book. Each image or set of images accompanies explanations of new or updated codes for reporting specific techniques and procedures. Topics range from general esophagectomy techniques, to differences in approach to minimally-invasive glaucoma surgery, to placement of a non-tunneling peripherally-inserted central catheter in a pediatric patient.

Esophagectomy

Shown is the process of detecting fetal trisomy with the use of cell-free DNA (cfDNA) in maternal plasma.The fragments are sequenced and aligned to a reference set of chromosome sequences. A counting process is then used to determine the relative amount of cfDNA from each chromosome and to investigate whether any are overrepresented. Overrepresentation of sequences from chromosome 21 suggests that the fetus has trisomy 21. N Engl J Med 2022; 387:1322-1324 DOI: 10.1056/NEJMcibr2209405

Keywords: Color, Education, Professional Education, Anatomy, Biology, Genetics, Maternal / Child, Reproductive Biology, Health & Wellness

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