AMI #25

Page 77

Amino Creative, LLC

medical illustration of Part of a collection of illustrations depicting key foundation principles, current challenges, and techniques in the field of lymphedema management. Published in Neligan P, et al. Lymphedema: Complete Medical and Surgical Management. Thieme. 2016.

Lymphatic system, fluid, swelling, lymph node, inner outer canthus, buccinator, preauricular, parotid, submandibular, inferior eyelid
medical illustration of Chylous ascites is a rare form of ascites that is characterized by the accumulation of protein-rich and chylomicron-rich lymphatic fluid in the peritoneal cavity. Lymph is generated from fluid that is squeezed out of the vasculature, filtered through the tissues, and then collected in the lymphatic ducts. N Engl J Med 2022; 386:1834-1844 DOI: 10.1056/NEJMcpc2115856
medical illustration of Part of a collection of illustrations depicting key foundation principles, current challenges, and techniques in the field of lymphedema management. Published in Neligan P, et al. Lymphedema: Complete Medical and Surgical Management. Thieme. 2016.
medical illustration of Part of a collection of illustrations depicting key foundation principles, current challenges, and techniques in the field of lymphedema management. Published in Neligan P, et al. Lymphedema: Complete Medical and Surgical Management. Thieme. 2016.
medical illustration of Part of a collection of illustrations depicting key foundation principles, current challenges, and techniques in the field of lymphedema management. Published in Neligan P, et al. Lymphedema: Complete Medical and Surgical Management. Thieme. 2016.
medical illustration of A protozoan parasite transmitted by the blood-feeding flies of the genus glossina (the tsetse fly), a vector that is widespread in sub-Saharan Africa. This parasite causes African trypanosomiasis (sleeping sickness), which is characterized by severe swelling of the lymph nodes, poor sleep, and neurologic, cognitive and psychiatric symptoms. In the absence of treatment, trypanosomiasis is fatal.
medical illustration of Shown is the process of detecting fetal trisomy with the use of cell-free DNA (cfDNA) in maternal plasma.The fragments are sequenced and aligned to a reference set of chromosome sequences. A counting process is then used to determine the relative amount of cfDNA from each chromosome and to investigate whether any are overrepresented. Overrepresentation of sequences from chromosome 21 suggests that the fetus has trisomy 21. N Engl J Med 2022; 387:1322-1324
DOI: 10.1056/NEJMcibr2209405
medical illustration of Images created for the AMA (Current Procedural Terminology) CPT Assistant Newsletter and the CPT Professional code book. Each image or set of images accompanies explanations of new or updated codes for reporting specific techniques and procedures. Topics range from general esophagectomy techniques, to differences in approach to minimally-invasive glaucoma surgery, to placement of a non-tunneling peripherally-inserted central catheter in a pediatric patient.
medical illustration of TTP is caused by severely low ADAMTS13 activity, leading to impaired cleavage of ultralarge von Willebrand factor multimers, platelet-rich microthrombi formation, and end-organ ischemia.  TTP is characterized by a relatively lower rate of renal failure and a relatively higher rate of severe thrombocytopenia and neurologic manifestations. N Engl J Med 2022; 387:e41. https://www.nejm.org/doi/full/10.1056/NEJMimc2117464
medical illustration of Panel A shows biofilms on the implant surface in a patient with an infected knee arthroplasty. Panel B shows common joint replacements. Panel C shows the external appearance of PJI of the knee, with swelling, erythema, a wound that is open at the bottom with drainage, and a sinus tract. Not all these clinical manifestations are present in every patient. N Engl J Med 2023; 388:251-262
DOI: 10.1056/NEJMra2203477.
medical animation of Series of illustrations created for a new video case series, NEJM Double Takes. This video highlights the effects of climate change on health through an illustrative patient case. Viewers are guided through the clinical presentation, differential diagnosis, laboratory studies, and treatment, culminating in the final diagnosis.
medical illustration of Screening for Atrial Fibrillation in Asymptomatic Older Adults. N Engl J Med 2022; 387:565-567
DOI: 10.1056/NEJMclde2203726
medical illustration of Oral Vancomycin as Secondary Prophylaxis for Prevention of Recurrent Clostridioides difficile Infection. N Engl J Med 2023; 388:654-656
DOI: 10.1056/NEJMclde2204692
medical illustration of Management of Hyperglycemia in Hospitalized, Non–Critically Ill Adults. N Engl J Med 2022; 387:1040-1042
DOI: 10.1056/NEJMclde2204691
medical illustration of Avoiding Contrast-Enhanced Imaging to Prevent Contrast-Induced Acute Kidney Injury. N Engl J Med 2022; 387:1809-1812
DOI: 10.1056/NEJMclde2204693
medical illustration of One of a series of images created for JAMA Dermatology's Patient Pages. The appearance and cause of various skin-related conditions are demonstrated.
medical illustration of An image created for a Rational Clinical Exam article discussing prevalence and evaluation for obstructive sleep apnea.
medical illustration of The rapid and simultaneous sequencing of DNA fragments derived from different genomes (of different organisms) in a single sample. Subsequent analysis of the resultant DNA sequences can reveal microbial composition and the presence of pathogens.
medical illustration of Library of gRNA is introduced into cells containing Cas9. RelA, which normally is located in the cytoplasm, is induced to move into the nucleus.. The stimulated cells are then sorted on the basis of correlation between the RelA intensity signal and a fluorescent nuclear stain. The two cell populations undergo sequencing for detection of gRNA. N Engl J Med 2022; 386:1755-1758
DOI: 10.1056/NEJMcibr2200971
medical illustration of One of a series of illustrations accompanying an article on xenotransplantation. This figure demonstrates the process of somatic cell nuclear transfer which permits derivation of genetically-modified animals, such as pigs. That process, in combination with additional ‘knock-in’ and ‘knock-out’ genes can produce organs that are less likely to elicit hyperimmune acute rejection when transferred to human recipients.
N Engl J Med 2022;387:35-44.
medical illustration of The first step in obtaining a clone of an organism. A somatic cell (or its nucleus) is obtained from the organism and transferred into the cytoplasm of an enucleated oocyte. Subsequent steps include reprogramming of the DNA in the nucleus by oocyte factors (a passive step) and induction of cell division through delivery of electric pulses.
medical illustration of One of a series of images created for the 2021 Lasker-DeBakey Clinical Medical Research Award honoring two scientists—Katalin Karikó (BioNTech) and Drew Weissman (University of Pennsylvania) and their discovery of a therapeutic technology based on the modification of messenger RNA. The images celebrate how their breakthrough was applied in the development of a highly effective Covid-19 vaccine strategy.
medical illustration of Illustration for the 2018 AMA (Current Procedural Terminology) CPT Assistant Newsletter and the CPT codebook. Accompanies an explanation of the new Cardiovascular codes 33927-33929 to report artificial heart system procedures.
medical illustration of A series of illustrations for a research article published in Structural Heart reviewing the anatomy of the heart's conduction system in the proximity of structural heart disease defects. The illustrations demonstrate how the anatomy in individuals with certain atrial and ventricular septal defects has clinical significance: undergoing percutaneous interventions can contribute to risk of developing inadvertent conduction disturbances.
medical illustration of A series of illustrations for a research article published in Structural Heart reviewing the anatomy of the heart's conduction system in the proximity of structural heart disease defects. The illustrations demonstrate how the anatomy in individuals with certain atrial and ventricular septal defects has clinical significance: undergoing percutaneous interventions can contribute to risk of developing inadvertent conduction disturbances.
medical illustration of A series of illustrations for a research article published in Structural Heart reviewing the anatomy of the heart's conduction system in the proximity of structural heart disease defects. The illustrations demonstrate how the anatomy in individuals with certain atrial and ventricular septal defects has clinical significance: undergoing percutaneous interventions can contribute to risk of developing inadvertent conduction disturbances.
medical illustration of Images created for the AMA (Current Procedural Terminology) CPT Assistant Newsletter and the CPT Professional code book. Each image or set of images accompanies explanations of new or updated codes for reporting specific techniques and procedures. Topics range from general esophagectomy techniques, to differences in approach to minimally-invasive glaucoma surgery, to placement of a non-tunneling peripherally-inserted central catheter in a pediatric patient.
medical illustration of A series of illustrations for PL Tonnard et al. Centrofacial Rejuvenation. Thieme. 2016.

The illustrations depict pertinent anatomy related to current facial augmentation and restorative techniques such as fat grafting and injection used to obtain more natural, stable rejuvenation results.
medical illustration of A series of illustrations for  PL Tonnard et al. Centrofacial Rejuvenation. Thieme. 2016.

The illustrations depict pertinent anatomy related to current facial augmentation and restorative techniques such as fat grafting and injection used to obtain more natural, stable rejuvenation results.
medical illustration of An image created for a Rational Clinical Exam article discussing prevalence and evaluation for obstructive sleep apnea.
medical illustration of A series of illustrations was created for a medical device company investigating a novel ablation approach using a high-power, low-current radiofrequency ablation catheter (Sphere-9/Affera, Inc) to create therapeutic focal lesions with adequate coverage and depth, with minimal-to-no injury to surrounding anatomy beyond the epicardium.
For comparison, the capabilities of a conventional ablation catheter in both thick and thin tissue applications was shown.
medical illustration of A series of illustrations was created for a medical device company investigating a novel ablation approach using a high-power, low-current radiofrequency ablation catheter (Sphere-9/Affera, Inc) to create therapeutic focal lesions with adequate coverage and depth, with minimal-to-no injury to surrounding anatomy beyond the epicardium.
For comparison, the capabilities of a conventional ablation catheter in both thick and thin tissue applications was shown.
medical illustration of An image created for a research article comparing treatments to reduce subsequent stroke complications in patients with carotid artery occlusion and hemodynamic cerebral ischemia.
JAMA. 2011;306(18):1983-1992.
medical illustration of An image created for a JAMA Patient Page on sciatica, showing the effect of a herniated disc on the sciatic nerve, the most common cause of sciatic nerve inflammation and pain.
JAMA. 2009;302(2):216.
medical illustration of An example of the 16 color-coded anatomical illustrations in Appendix L of AMA's CPT codebook: an extensive table and illustrations series that serves as a reference for the interventional radiology code section. Collectively, they display the hierarchy of vascular branching, with major arteries and veins (aorta, vena cava, pulmonary artery, or portal vein) as the starting point of catheterization.
medical illustration of Images created for the AMA (Current Procedural Terminology) CPT Assistant Newsletter and the CPT Professional code book. Each image or set of images accompanies explanations of new or updated codes for reporting specific techniques and procedures. Topics range from general esophagectomy techniques, to differences in approach to minimally-invasive glaucoma surgery, to placement of a non-tunneling peripherally-inserted central catheter in a pediatric patient.
medical illustration of This extensive table and series of illustrations serve as a reference for the interventional radiology code section. Collectively, they display the hierarchy of vascular branching, with major arteries and veins (aorta, vena cava, pulmonary artery, or portal vein) as the starting point of catheterization.
medical illustration of A series of illustrations created for the Wisdom Wrap® product packaging insert.
This hot/cold gel pack therapy product has a unique variety of applications; these illustrations describe the steps to achieve optimum use.
medical illustration of A series of illustrations created for the Wisdom Wrap® product packaging insert.
This hot/cold gel pack therapy product has a unique variety of applications; these illustrations describe the steps to achieve optimum use.
medical illustration of This illustration accompanies an article published in ACS Nano. It features many issues at the interface between
medical illustration of The illustration serves as an overview of the key influential forces in nanomaterial engineering, current oncology research—and, to highlight ways to improve the next-generation of nanomedicines—also draws focus to existing controversies, and emerging concepts and opportunities for tumor targeting and clinical impact.
medical illustration of An image created for a JAMA Patient page on summer safety for kids.
JAMA. 2013;309(23):2505.
medical illustration of One of 30+ cover images for JAMA. The Jan 16, 2018 issue of the Journal of the American Medical Association, dedicated to research and reviews on the current status of obesity management and long-term care. 
The image focuses on aspects of diet decision-making and food choices, by 'expanding' a few common foods and beverages into their key components and caloric content.
medical illustration of An image created for a JAMA Patient Page on hemolytic uremic syndrome and the risks of exposure to E. coli.
medical animation of This video is one in a series of educational videos produced for a bio-nutrient company that focuses on sustainable plant nutrition. It introduces the basics of soil health, and is used to highlight key mechanistic advantages of the company's products and formulations in the areas of soil chemistry, soil biology, and plant physiology. The video is utilized in an educational lecture/presentational setting for sales representatives, customers, and distributors.
medical illustration of 50+ images created for a Google Health initiative. We joined a team of medical illustrators, physicians, and other medical content experts to make 400 medical and health conditions, aesthetically and informationally approachable. Accompanies the 'knowledge panel' displayed in Google search results for health conditions.
We also helped lay the initial groundwork to develop the stylistic appearance, and consulted on narrative development and other supporting conceptual material.
medical illustration of 50+ images created for a Google Health initiative. We joined a team of medical illustrators, physicians, and other medical content experts to make 400 medical and health conditions, aesthetically and informationally approachable. Accompanies the 'knowledge panel' displayed in Google search results for health conditions.
We also helped lay the initial groundwork to develop the stylistic appearance, and consulted on narrative development and other supporting conceptual material.
medical illustration of 50+ images created for a Google Health initiative. We joined a team of medical illustrators, physicians, and other medical content experts to make 400 medical and health conditions, aesthetically and informationally approachable. Accompanies the 'knowledge panel' displayed in Google search results for health conditions.
We also helped lay the initial groundwork to develop the stylistic appearance, and consulted on narrative development and other supporting conceptual material.
medical illustration of 50+ images created for a Google Health initiative. We joined a team of medical illustrators, physicians, and other medical content experts to make 400 medical and health conditions, aesthetically and informationally approachable. Accompanies the 'knowledge panel' displayed in Google search results for health conditions.
We also helped lay the initial groundwork to develop the stylistic appearance, and consulted on narrative development and other supporting conceptual material.
medical illustration of 50+ images created for a Google Health initiative. We joined a team of medical illustrators, physicians, and other medical content experts to make 400 medical and health conditions, aesthetically and informationally approachable. Accompanies the 'knowledge panel' displayed in Google search results for health conditions.
We also helped lay the initial groundwork to develop the stylistic appearance, and consulted on narrative development and other supporting conceptual material.
medical illustration of An editorial image for an article in JAMA's Medical News and Perspectives section on an FDA warning about 70 over-the-counter diet products that may contain undeclared, dangerous drugs.
JAMA. 2009;301(8):817
medical illustration of One of 30+ cover images for JAMA. The Jan 23, 2013 issue of the Journal of the American Medical Association, dedicated to research and reviews on the current quality and cost approaches to reducing hospital readmission.
The image draws inspiration from MC Escher's work ('Ascending and Descending'), creating an endless loop to readmission—a relevant issue for CMS and Medicare reimbursement.
medical illustration of An editorial image for an article in JAMA‘s Medical News and Perspectives section on surrounding FDA’s position on bisphenol A (BPA) safety, and legislators’ concerns over the chemical leading to diabetes, cancer, and obesity.
medical illustration of One of several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of Several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of One of several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of One of several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of One of several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of Several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of One of several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of Several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of A series of illustrations for The Harris Orthopaedic Laboratory @ The Mass General by William H. Harris, MD.
medical illustration of One of several hundred illustrations for The Secret of Life, the digital textbook for MIT’s on-campus course 7.012 and online course 7.00x on Introductory Biology. The course is taught by Eric Lander, president and founding director of the Broad Institute, and professor of biology.
medical illustration of Color, Education, Publishing, Biology, Biotechnology

Profile

For almost two decades, the founders of Amino Creative—Alison E. Burke and Cassio Lynm—have enjoyed a productive collaboration that began at a Chicago-based medical publisher. Together, they bring nearly 40 years of combined experience to the table, with the ability to create novel illustrations and multimedia features for a variety of audiences—physicians, clinicians, researchers, scientists, allied health professionals, medical students, patients, and the general public. At Amino Creative, our specialty is communicating science and medicine, but we can help explain much more. We tackle the interesting, the unique, and the unusual…welcoming projects that challenge our technical, conceptual, and creative skills as artists and visual communicators.

Style/Techniques

Black & White, Cartoon, Color, Caricature, Information Graphics, Line with Color, Video, Microscopy

Subject/Specialties

Allergy / Immunology, Anatomy, Biology, Biotechnology, Botany, Cardiac Surgery / Cardiology, Cell biology / Histology, Dermatology, Disease Management, Embryology, Emergency Medicine, Endocrinology / Metabolic, Entomology, General Medicine, General Surgery, Genetics, Maternal / Child, Medical Devices, Molecular Biology, Natural Science / Nature, Neuroscience, Neurosurgery, Obstetrics / Gynecology, Ophthalmology, Orthopaedics, Pediatrics, Pharmacology, Reconstructive Surgery, Portraits, Reproductive Biology, Thoracic Surgery, Transplantation Surgery, Vascular Surgery, Veterinary Medicine, Virology, Zoology, Oncology, Health & Wellness, Pathology, Plastic Surgery, Sports Medicine