Lila Strohl

Vagus Nerve Recording with CorTec Cuff Electrode 

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Cells of the Dentate Gyrus

medical illustration of Vagus nerve recording with CorTec cuff electrode in a mouse
Next medical illustration of Proposed innate immunity mechanism of action for anti-CD47 antibodies. Blocking the CD47/SIRP-a “don’t eat me” signal between tumor cells and antigen-presenting phagocytic cells (APCs) results in phagocytosis of the tumor cell and cross-presentation of antigens derived from the tumor cell via MHC class I to T cells, which then are induced to produce apoptotic factors that can kill tumor cells directly.

Innate Immunity MOA for Anti-CD47 Antibodies

Vagus nerve recording with CorTec cuff electrode in a mouse

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© Joshua J. Strohl PhD