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Woodhead Publishing Series in Biomedicine

Therapeutic Antibody Engineering

Next Image Title

Artist Name

W.R. Strohl and L.M. Strohl, 2012

AMI #28

Page 153

AMI #27

Page 66

AMI #26

Page 147

medical illustration of IgM antibody binding a CD20 receptor expressed on a B cancer cell and a CD3 receptor expressed on a T cell
medical illustration of A model of the surface of a SARS-CoV-2 virion showing SARS-CoV-2 spike proteins with one open RBD or all closed RDBs based on PDB ID 6VYB and 6VXX, respectively. The antibodies shown include IgGs (PDB ID 1IGT) crosslinking two spikes and an IgM (based on PDB ID 2RCJ) binding to multiple spikes. Also depicted is a domain antibody trimeric VHH-Fc fusion protein (based on PDB IDs 6ZXN and 1IGT) cross-linking spikes and individual VHHs (PDB ID 6ZXN) binding to RBDs with no cross-linking ability.
medical illustration of Macrophages attacking S. pneumoniae in pulmonary alveoli
medical illustration of Proposed innate immunity mechanism of action for anti-CD47 antibodies.  Blocking the 
CD47/SIRP-a “don’t eat me” signal between tumor cells and antigen-presenting phagocytic cells (APCs) results in phagocytosis of the tumor cell and cross-presentation of antigens derived from the tumor cell via MHC class I to  T cells, which then are induced to produce apoptotic factors that can kill tumor cells directly.
medical illustration of Three signals dominate the
medical illustration of SIRP-a, which is on the surface of phagocytes, normally binds CD47 on the surface of normal and tumor cells as a signal to prevent phagocytosis (often referred to as the “don’t eat me” signal).  Blocking the CD47/SIRP-a interaction with a monoclonal antibody can result in a pro-phagocytic response (i.e., the cancer cells can become phagocytized).
medical illustration of Antagonist IgG antibody binding to the immuno-oncology checkpoint target, PD-1, to reinvigorate exhausted T cells
medical illustration of IgG Antibody
medical illustration of Artistic representation of antibodies coming in for a landing and binding to receptors on the surface of a B cell
medical illustration of Dentate Pyramidal Basket Cell and Granule Cells
medical illustration of Vagus nerve recording with CorTec cuff electrode in a mouse


Lila Strohl is a board Certified Medical Illustrator and a member of the Association of Medical Illustrators since 1993. Lila received a Bachelor of Science in Allied Health Professions in 1978 from The Ohio State University, The School of Allied Medical Professions-The College of Medicine. Her past experience includes work as Head of Medical Illustration at St. Anthony Medical Center, Columbus, Ohio (1978-1986), work as a staff Medical Illustrator in the department of Biomedical Communications at The Ohio State University (1987-1988), and owner of Medcom Graphics, a sole proprietorship that specialized in medical-legal work in Columbus, Ohio (1989-1997) and medical and scientific illustration in Bridgewater, New Jersey (1998-2008). Lila's work experience is diverse and includes working with surgeons, scientists, law firms, universities, publishers and biotech companies. Lila is currently the owner of Biomedscapes (2008-present), a medical and scientific art company in Bridgewater, New Jersey. Biomedscapes specializes in the creation of scientific and medical illustrations depicting cellular and molecular landscapes and information graphics for immunology, cell and molecular biology, biotechnology, pharmacology and medicine.


Airbrush, Color, Information Graphics


Allergy / Immunology, Biology, Biotechnology, Cell biology / Histology, Genetics, Molecular Biology, Neuroscience, Neurosurgery, Pharmacology, Virology, Oncology, Mechanism of Action (MOA), Pathology