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The Role of CGRP in Migraine Pathogenesis 

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CGRP in Migraine Hologram Medical Animation

medical illustration of This animation laid the foundation disease awareness story for the first new migraine drug in decades: Aimovig (erenumab). It begins with the burden of disease of migraine, moves through pathophysiology, then dives into the story of a key molecular player: CGRP.  A thorough review of the migraine literature informed the script and visuals. All models and anatomy are data-driven.
Next medical illustration of What better way to educate a headache specialist on the role of CGRP in migraine than to show it in their own brain! Utilizing live video tracking, we programmed MiBrain to simulate a live scan so that neuro and vascular anatomy on the screen track a user’s movements. We leverage experiential learning by showing CGRP and its receptor in structures that appear to be inside a user’s head. A photo printout puts smiles on faces and reinforces key messages.

MiBrain Interactive Photo Booth

This animation laid the foundation disease awareness story for the first new migraine drug in decades: Aimovig (erenumab). It begins with the burden of disease of migraine, moves through pathophysiology, then dives into the story of a key molecular player: CGRP. A thorough review of the migraine literature informed the script and visuals. All models and anatomy are data-driven.

Keywords: Animation, 3D, Anatomy, Molecular Biology, Neuroscience, Pharmacology, Mechanism of Action (MOA), Pathology

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