KAUST

DNA Replication of the lagging strand

Nanographics

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DNA replication is a process in our cells that is essential to our survival. This visualization shows incredible molecular machinery that makes DNA replication possible. See the full video here: https://www.youtube.com/watch?v=KwIxV4duUes

nanographics

Nanographics

medical illustration of A hand-drawn illustration shows a human brain, larynx, rib cage, and heart.
medical illustration of A hand-drawn illustration of the median sagittal section of the human brain. Various anatomical structures are labeled. Ball-point pen.
medical illustration of The picture promotes excellent research by Cvetkovic et al. about the initiation of DNA replication published in this journal issue.
medical animation of Viruses are very small. One thousand of them lined up next to each other would be as thick as a single hair. When scientists look for ways how to fight a virus, they use detailed 3D models. But can we see a virus for real? With cryo-em tomography and the visualization technology developed at nanographics, we can!
medical animation of The model in this video represents the current understanding of the molecular composition of SARS-CoV-2, including the latest theory on how genetic information is organized inside the virus particle. We teamed up with researchers from Scripps Research and KAUST who provided us with the biological data. We imported the model into our real-time molecular-visualization software, where we composed the final video. Indeed, what you see here is all rendered in real-time.
medical animation of DNA replication is one of the most essential tasks of the human body. This animation shows the molecular machinery which fills in the Okazaki fragments during the replication of the lagging strand.
medical animation of A 3D animation of acetylcholine interacting with a receptor embedded in a bi-lipid membrane of a muscle cell where an impulse from a neuron is transmitted.
medical animation of This video shows a mechanism of action of enzyme aging in acetylcholinesterase.
medical animation of An animation showing antibodies attaching to spike proteins of a SARS-CoV-2 virion, disabling it.
medical animation of Microtubules are long, hollow tubes present in each of your cells. They help to maintain the shape of the cell, and they form rails along which material is transported throughout the cell. They even help with the cell division. In this video, we show you how microtubules assemble from molecules of proteins randomly scattered throughout every cell. The video has been rendered with a real-time molecular visualization engine Marion and real-time composition library Vj made by nanographics.
medical animation of We made an illustration of a life-cycle of a virus. It shows how the proteins of the viral envelope interact with the proteins of the cell membrane to allow the virion to enter the cell. But how to show proteins, virions, and cells, whose sizes are orders of magnitude apart, in a single picture? We made this video to give a little insight into our thought process when creating the illustration.
medical animation of In this video, we show you some of the volume rendering techniques we have implemented over the years in Marion, our scientific visualization library. We put the video together using our real-time composition library Vj.
medical animation of This real-time visualization of an HIV particle in atomistic detail has been rendered by our in-house software Marion.
medical illustration of Each hexagon shows a molecular detail of one specific part of a cell. The name of the molecular structure is highlighted in bold, while the part of the cell it belongs to is underlined.
medical illustration of The human body is a marvel of nature. It is powered by countless molecular machines that work in perfect sync to keep us alive. In the center of it all is DNA - a molecule that encodes the blueprint for all of this incredible machinery. Since each cell of our body (except for red blood cells) has a copy, DNA replication is one of the most essential tasks on the molecular scale.
medical illustration of This is a still image from an animation showing the mechanism of action of acetylcholine (shown in orange with a white outline). The green molecule is an acetylcholine receptor, to which acetylcholine binds when a neural impulse is transferred from a neuron to a muscle cell.
medical illustration of DNA replication is one of the most essential tasks of the human body. This image shows the molecular machinery which fills in the Okazaki fragments during the replication of the lagging strand.
medical illustration of DNA replication is one of the most essential tasks of the human body. This image shows a nucleotide before it is incorporated into the DNA molecule.
medical illustration of This image is a still from an animation showing DNA replication of the lagging strand. The image shows a high-fidelity, procedurally generated 3D model of the DNA molecule.
medical illustration of This image shows the insides of a ribosome while translating mRNA into a protein. The blue, green, and red molecules are tRNA in various stages of the process. The newly-formed protein is shown in yellow. This is a part of an interactive installation where visitors can explore the process on a large touch-enabled surface.
medical illustration of A rendering of a macrophage cell stylized as a scanning electron micrograph. Made in Blender.
medical illustration of Microtubules are long, hollow tubes present in each of your cells. They help to maintain the shape of the cell, and they form rails along which material is transported throughout the cell. They even help with cell division. This image is a still from an animation showing how microtubules assemble from protein molecules randomly scattered throughout every cell. The animation has been rendered in real-time with our in-house molecular rendering engine Marion.
medical illustration of Microtubules are long, hollow tubes present in each of your cells. They help to maintain the shape of the cell, and they form rails along which material is transported throughout the cell. They even help with cell division. This image is a still from an animation showing how microtubules assemble from protein molecules randomly scattered throughout every cell. The animation has been rendered in real-time with our in-house molecular rendering engine Marion.
medical illustration of Microtubules are long, hollow tubes present in each of your cells. They help to maintain the shape of the cell, and they form rails along which material is transported throughout the cell. They even help with cell division. This image is a still from an animation showing how microtubules assemble from protein molecules randomly scattered throughout every cell. The animation has been rendered in real-time with our in-house molecular rendering engine Marion.
medical illustration of Microtubules are long, hollow tubes present in each of your cells. They help to maintain the shape of the cell, and they form rails along which material is transported throughout the cell. They even help with cell division. This image is a still from an animation showing tubulin - a building block from which microtubules are assembled. The animation has been rendered in real-time with our in-house molecular rendering engine Marion.
medical illustration of This is a model of a HIV virion submerged in blood plasma in atomistic resolution. The model has been rendered in real-time with our in-house rendering engine, Marion. The illustrative style helps to distinguish individual protein molecules from each other, while it maintains the complexity of the original model.
medical illustration of This image shows three stages of endocytosis of a SARS-CoV-2 virion. First, the virion attaches its spike protein to an ACE2 embedded in a cell membrane. The cell then encloses the virion with part of its membrane and brings it inside. The enclosure is then merged with the membrane of the virion, and the content of the virion is ejected into the cell's cytoplasm.
medical illustration of This illustration shows antibodies attaching to the spike proteins of a SARS-CoV-2 virion and thus disabling it. It is part of an interactive installation where the visitors can explore the process on a large touch-enabled surface.
medical illustration of An illustration of respiratory droplets carrying virions of SARS-CoV-2. Made in Blender
medical illustration of An atomistic model of SARS-CoV-2 rendered in real-time with our in-house rendering engine Marion.
medical illustration of An atomistic model of SARS-CoV-2 rendered in real-time with our in-house rendering engine Marion. The image shows how the RNA is organized inside the virion.
medical illustration of A virion of SARS-CoV-2 enters an epithelial cell by attaching its spike protein to the cell's ACE2 receptor. The virion then enters the cell (as seen in the background) and reprograms its machinery to make copies of the virus. The newly built virions then exit the cell by capturing its membrane, as seen further in the background. This image shows, through a forced perspective, an entire life-cycle of a virus.
medical illustration of A virion of SARS-CoV-2 enters an epithelial cell by attaching its spike protein to the cell's ACE2 receptor. The virion then enters the cell (as seen in the background) and reprograms its machinery to make copies of the virus. The newly built virions then exit the cell by capturing its membrane, as seen further in the background. This image shows, through a forced perspective, an entire life cycle of a virus. This image shows an initial sketch and the final rendering of the illustration.
medical illustration of Several variations of a real-time volumetric rendering of a CT scan of a stag beetle. Various lighting effects and transfer functions are used to simulate several different styles. The images are rendered in our real-time visualization framework Marion.
medical illustration of A 3D rendering of vaccine vials. Made in Blender.
medical illustration of This image shows a cell surface covered by many virus particles (virions). The rendering is stylized to resemble electron microscope images. Made in Blender.
medical illustration of This is an electron cryotomography scan of real SARS-CoV-2 virions. With our in-house visualization software, we were able to visualize this scan in unprecedented detail, giving researchers and the public a unique view of particles of a virus responsible for the global pandemic of Covid-19.
medical illustration of This is an electron cryotomography scan of a real SARS-CoV-2 virion. With our in-house visualization software, we were able to visualize this scan in unprecedented detail, giving researchers and the public a unique view of particles of a virus responsible for the global pandemic of Covid-19.

Style/Techniques

Animation, Airbrush, Black & White, Cartoon, Color, Design, Information Graphics, 3D, Models, Video, Microscopy, VR/Virtual Reality

Subject/Specialties

Allergy / Immunology, Anatomy, Biology, Biotechnology, Cell biology / Histology, Molecular Biology, Orthopaedics, Virology, Mechanism of Action (MOA), Pathology