Biological Psychiatry

Tracking development of connectivity in the human brain: axons and dendrite

Jane Whitney

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Axons consist of neurofilaments (in green) and microtubules (in red). Neurofilaments set the axon diameter and, in interaction with myelin in myelinated axons, co-determine g ratio. Microtubules provide the structural foundation for axonal transport; in this illustration, a motor protein (kinesin-1) moves a cargo in the anterograde direction, from the cell body to the presynaptic terminal. By Tomáš Paus

BiologicalPsychiatry

Jane Whitney

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medical illustration of Delivering cancer-killing Docetaxel directly into cancer cells: Method-of-action for delivery into the cell using a drug conjugate. The pharmaceutical company used this in a powerpoint slide deck. I provided the illustration in powerpoint, with items separated and the labels added in powerpoint.
medical illustration of Axons consist of neurofilaments (in green) and microtubules (in red). Neurofilaments set the axon diameter and, in interaction with myelin in myelinated axons, co-determine g ratio. Microtubules provide the structural foundation for axonal transport; in this illustration, a motor protein (kinesin-1) moves a cargo in the anterograde direction, from the cell body to the presynaptic terminal.
medical illustration of For Fatal Jump: Tracking the Origins of Pandemics. Various coronaviruses, including COVID, have made the jump from wild to domestic animals, then to humans.
medical illustration of The COVID-19 virus, Sars-CoV-2, is an RNA virus which replicates in the cytoplasm of the host cell, using the host's ribosomes.
medical illustration of BOTOX is indicated for bladder dysfunction, including: Neurogenic detrusor overactivity associated with a neurological condition, and Overactive bladder
medical illustration of This upcoming book by Neil Baum, M.D was written to serve as a tool and a road map for partners who have men with prostate cancer. The author wanted a unique view and simple anatomy showing the nerves of the male pelvis, with an emphasis on the pudendal nerves.
medical illustration of From the upcoming book: Honest Aging - An Insider's Guide to the Second Half of Life, by Rosanne M. Leipzig, MD, PhD
medical illustration of Just published: Weight Loss for Life: The Proven Plan for Success by Kimberly A. Gudzune and Lawrence J. Cheskin. This image shows
medical illustration of For the upcoming book,
medical illustration of The general structure of a ‘membrane fat’ where two fatty acids are attached to a head group. Both omega-6 and omega-3 are essential in the human diet and together these two types of polyunsaturated fats are also called “essential fatty acids”
medical illustration of For an upcoming book on dementia by Emily Clionsky, MD. A major consequence of obstructive sleep apnea is impaired cognitive functioning.
medical illustration of Administering Subcutaneous injections for ovulation induction segment of IVF cycle. For an upcoming book on infertility by Joseph Sanfilippo, MD.
medical illustration of The hypothalamic-pituitary axis involves both negative and positive feedback mechanisms in the female. For an upcoming book on infertility by Joseph Sanfilippo, MD.
medical illustration of A variety of medical treatments are available for abnormal vaginal bleeding. For an upcoming book on infertility by Joseph Sanfilippo, MD.
medical illustration of Invasive EEG monitoring is a test to pinpoint where seizures start in the brain. For the upcoming book, Seizures and Epilepsy in Children, by Eileen P.G. Vining, M.D.
medical illustration of Locations of lung cancer of lung cancer in patients with a certain chromosomal rearrangement. Created for a powerpoint presentation for a pharmaceutical company.
medical illustration of The SARS-CoV-2 virus, which causes the COVID-19 disease. The spike on the virus binds to the ACE2 receptor on the surface of the alveolar type 2 cell in the lung.
medical illustration of Celsion’s next generation vaccine delivers, on a single plasmid, multiple SARS-CoV-2 antigens in conjunction with a potent immune modifier, interleukin-12 (IL-12), which directs a TH-1 immune response, stimulates T-cell immunity, and also promises the promotion of humoral immunity (antibody response). Celsion has taken this multivalent approach in an effort to generate an even more robust immune response.
medical illustration of The primary intraparenchymal meningioma of the frontal lobe with no apparent dural attachment. The presumption is that arachnoid cells present in the pia mater migrate together with penetrating blood vessels during brain development. World Neurosurgery, Sept. 2021
medical illustration of Fourth ventricle roof angle as a measure of fourth ventricle bowing and a radiographic predictor of brainstem dysfunction in Chiari malformation type I Accepted to Journal of Neurosurgery: Pediatrics
medical illustration of Pneumorrhachis: The most frequent initial mechanism is an increase in intraalveolar pressure (acute asthma, recurrent vomiting, or closed thoracic trauma). Barotrauma and alveolar rupture allow air migration along the bronchial tree up to the mediastinum. The collected air then separates the mediastinal pleura from the aorta and the parietal pleura from the spine; therefore, it enters the epidural space via the intervertebral foramina.
medical illustration of In rare cases the embryonic foramen caecum is not obliterated and the dural diverticulum does not retract. In this pediatric case an intracranial connection required surgery to remove the tract and 2 cysts.
medical illustration of An illustration for a patient book for the drug Abraxane, for the treatment of pancreatic cancer.
medical illustration of LH-stimulated changes in capillary growth and leukocyte delivery in the ovulatory follicle. Immune cells are present in the ovarian vasculature and theca interna of the preovulatory follicle (top). New vessels and breakdown of the granulosa cell basal lamina provide points of entry for circulating leukocytes (center). Additional leukocytes are seen in the granulosa cell layer prior to ovulation (bottom). Leukocyte-secreted chemokines and cytokines increase as ovulation approaches.
medical illustration of Cover illustration, June 2020, Journal of Neurosurgery: Pediatrics. A spinal extradural arachnoid cyst (SEAC) results from a rare small defect of the dura matter.
medical illustration of Procedure for drainage of a cyst in the third ventricle. The peel apart introducer allows a catheter to be inserted after the endoscope has been used to visualize the path and create a hole in the cyst. Then the catheter can be inserted.
medical illustration of Menstruation occurs after the functionalis layer of endometrium separates from the basalis. It is plausible to hypothesize that the separation between the two layers at a relatively superficial plane may lessen the likelihood of heavy bleeding or travel of stem cells into the pelvic cavity. Separation at a deeper plane, however, may favor the endometriosis phenotype.
medical illustration of Drawing of a section of the seminiferous tubule, showing the testosterone-producing Leydig cells, supporting Sertoli cells and the developing sperm. As cells mature, they progress toward the lumen of the seminiferous tubule.
medical illustration of The most common position of the uterus is anteverted (cervix angles forward) and anteflexed (body is flexed forward). A retroverted uterus is angled slightly posterior.
medical illustration of About 5–6 days post-fertilization the blastocyst usually reaches the uterus, and begins to embed into the endometrium of the uterine wall. The blastocyst possesses an inner cell mass which subsequently forms the embryo.
medical illustration of Insulin pumps are indicated for the continuous delivery of insulin, at set and variable rates, for the management of diabetes mellitus in persons requiring insulin.
medical illustration of Endoscopic approach to the posterior fossa.
medical illustration of Schematic overview of the human hypothalamus. Craniopharyngiomas most likely arise from epithelial remnants of the craniopharyngeal duct or the Rathke pouch (light yellow bar). The hypothalamus consists of many hypothalamic nuclei, which are all highly connected through neural pathways. The connection between the arcuate nucleus and paraventricular nucleus (PVN) is emphasized.
medical illustration of An illustration of the general anatomy of the tentorium and relationships with the sinuses and skull.
medical illustration of One in a series of 30 illustrations for a training manual for Remodulin. The illustrations show step by step how to fill a Remodulin pump.
medical illustration of Eye section showing the cornea, iris, and lens, for a grade 8 science textbook.
medical illustration of In this procedure the stapes is cut, leaving the foot plate. A hole is drilled in the foot plate and a prosthetic stapes is attached to the incus.
medical illustration of Repair of giant anterior skull base encephalocele containing intralesional eloquent brain
medical illustration of Anatomy and surgical approach in endoscopic third ventriculostomy for the relief of hydrocephalus.
medical illustration of Brighter Than You Think is about those Eureka! or Aha! moments. Intelligent memory is needed in creative or critical thinking, and used in creating more sophisticated thinking. It is about making creative connections - connecting the dots - connecting pieces of information to come up with an idea.
medical illustration of Color, Education, Web, Anatomy, Biology, Embryology
medical illustration of Development of the embryonic urinary system at 5 weeks.
medical illustration of The celiac artery and its branches.
medical illustration of Color, Education, Web, Biology, Cell biology / Histology, Genetics, Molecular Biology, Natural Science / Nature
medical illustration of Color, 3D, Education, Web, Cell biology / Histology, Molecular Biology
medical illustration of Color, Education, Web, Cell biology / Histology, Molecular Biology
medical illustration of Color, 3D, Education, Publishing, Web, Biology, Cell biology / Histology, Molecular Biology
medical illustration of Color, Line with Color, Education, Biology, Genetics
medical illustration of Color, Education

Profile

Jane Whitney CMI has been providing professional medical and scientific illustration services for journals, education, and patient information since 1988. Her illustration style focuses first on clarity, explaining concepts and structures in the best possible way for her client’s audience. Jane uses Adobe Illustrator and Photoshop for her digital illustrations. Jane also provides art development editing services. Her combination of art and scientific knowledge have bridged communication between the editorial team and illustrator/animator for Pearson Education, the cementbloc, and WiseWire. Based in Toronto, Jane’s client list includes educational publishers and ad agencies both in Canada and the United States. Education: Ontario College of Art and Design. B.Sc., Art as Applied to Medicine, University of Toronto, 1988. Certified Medical Illustrator, 2021.

Style/Techniques

Black & White, Color, Information Graphics, Line, Line with Color, 3D

Subject/Specialties

Allergy / Immunology, Anatomy, Biology, Biotechnology, Cell biology / Histology, Disease Management, Embryology, Endocrinology / Metabolic, General Medicine, General Surgery, Genetics, Maternal / Child, Medical Devices, Molecular Biology, Natural Science / Nature, Neuroscience, Neurosurgery, Obstetrics / Gynecology, Ophthalmology, Orthopaedics, Pediatrics, Pharmacology, Reconstructive Surgery, Reproductive Biology, Respiratory, Urology, Virology, Injuries, Oncology, Mechanism of Action (MOA), Health & Wellness, Plastic Surgery