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Lila Strohl

Lila Strohl

IgM Antibody Simultaneously Binding CD20 and CD3

Vagus Nerve Recording with CorTec Cuff Electrode

medical illustration of IgM antibody binding a CD20 receptor expressed on a B cancer cell and a CD3 receptor expressed on a T cell

medical illustration of A model of the surface of a SARS-CoV-2 virion showing SARS-CoV-2 spike proteins with one open RBD or all closed RDBs based on PDB ID 6VYB and 6VXX, respectively. The antibodies shown include IgGs (PDB ID 1IGT) crosslinking two spikes and an IgM (based on PDB ID 2RCJ) binding to multiple spikes. Also depicted is a domain antibody trimeric VHH-Fc fusion protein (based on PDB IDs 6ZXN and 1IGT) cross-linking spikes and individual VHHs (PDB ID 6ZXN) binding to RBDs with no cross-linking ability.

Model of SARS-CoV-2 Targeted by Antibodies

IgM antibody binding a CD20 receptor expressed on a B cancer cell and a CD3 receptor expressed on a T cell

Keywords: Airbrush, Color, Publishing, Web, Professional Education, Research, Biotechnology, Cell biology / Histology, Molecular Biology, Mechanism of Action (MOA)

© Lila Strohl