Heartware

VAD Medical Device Animation

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This animation was made to introduce cardiac surgeons and other stakeholders to the HeartWare System, its use and key technological advantages. It was important to clearly illustrate the pump’s proprietary suspension system, which eliminates wear. To focus viewer attention, we rendered the system and heart photorealistically and used a simpler illustrative style for supporting elements.

AXS Studio Inc.
medical animation of This general showreel by top medical animation company AXS Studio, features 3D medical animation for pharma, biopharma, biotech, medical device, medtech & healthcare. It includes apps, games, conference booth experiences, pharmacology, biotechnology, antibody-drug conjugates, ADC, multiple myeloma, atrial fibrillation, cardiac ablation, cystic fibrosis, VR, migraine, minimal residual disease, biosimilars, diagnostics, CRISPR Cas9, COVID-19, SARS CoV-2, tumor, breast cancer & angiogenesis.
medical animation of 3D medical animation about heart failure, HFrEF, for professional education. Sarcomere mechanics, showing the complex steps of the actin-myosin cross-bridge cycle in muscle contraction. Molecular animation, 3D scientific animation. Disease state awareness video, DSE animation, MOD animation, mechanism of action animation; scientific animation; cardiology, heart animation, heart health animation, anatomy. Visit https://www.axs3d.com
medical animation of 2022 AMI Award winner. Innovative medical animation created to educate HCPs on the role of CARD11-BCL10-MALT1, or CBM, in cancer & introduce the MOA of CBM inhibitor, XL114. An animated schematic explains how CBM bridges B-cell and T-cell receptor signaling to the NF-κB pathway. Molecules were modeled using protein structure data & mapped according to subcellular localization data. MOA animation, mechanism of action, scientific animation, mograph, motion graphics, datavis, pharmacology.
medical animation of Targeting PDE4 with topical drugs has been unsuccessful due to the difficulty in crossing the epidermis. A novel formulation of roflumilast facilitates drug delivery to the inflammatory cells of psoriasis. We worked with Arcutis scientists & devised a visual model of roflumilast emulsions. Features: lipid matrix, skin cells, epidermis, dermis, corneocytes, stratum corneum, pharma MOA, pharmaceutical MOA animation, drug MOA, dermatology, plaque psoriasis, pharmacology.
medical illustration of Nature's creative director and the manuscripts' authors envisioned a single scene depicting a diversity of cells: human and microbe. We researched over 35 cell types mentioned in three featured studies to ensure accuracy of scale and form. We took our inspiration from coral reefs, creating a scene that was a riot of color, shapes and textures to convey the idea of diversity of the biome. Translucency and an overall underwater feel were used to give the impression of a fantastic voyage.
medical animation of Unique experiences for medical & scientific congress / conference exhibit booths, detail aids & product demonstrations by top medical interactive company AXS Studio, www.axs3d.com. For pharma, biopharma, biotech, medical device & healthcare. Mobile apps, educational games, serious games, interactive virtual reality, VR, augmented reality, AR, mixed reality, MR, user experience, UX, design, disease state simulators & holograms. https://axs3d.com/services/interactive-apps-and-experiences/
medical illustration of This website interactive allows students to explore and learn about a biotechnology tool that is at the forefront of scientific research and hear directly from leading researchers about how they use CRISPR-Cas9. Created in collaboration with Tangled Bank Studios, Howard Hughes Medical Institute (HHMI). Winner of the Award of Excellence, 2018 annual meeting of the Association of Medical Illustrators.
medical animation of Medical virtual reality, VR, experience immerses headache specialists in the biology of migraine. In a virtual scavenger hunt, participants explore the molecular mechanism of disease, MOD, at anatomical sites & collect badges by answering quiz questions. Physical 3D brain serves as centerpiece, bridging real & virtual worlds at scientific congress booth. Analytics tracks HCP knowledge gaps. Neurology, neuroscience, anatomy, CNS, DSE, disease state education.
medical illustration of We created this amazing interactive experience to let rheumatologists peer inside their own hands to witness the signs and symptoms of psoriatic arthritis (PsA) at three stages of involvement: skin; early joint; and progressive joint. Scanning modes simulated imaging techniques used in diagnosis. The result: a huge increase in HCP traffic and engagement for our client at their exhibit booths.
medical animation of A medical device iPad app to show eyecare practitioners how Optejet works. An
medical animation of This showreel by top medical animation company AXS Studio, www.axs3d.com, features: biotechnology, biotech, medtech, medical device, pharmaceutical & patient education animation. Topics include: antibody-drug conjugates, ADC, multiple myeloma, cystic fibrosis, lung cancer, breast cancer, liver cancer, bone cancer, brain cancer, skin cancer, melanoma, tumor, immunotherapy, muscle, angiogenesis, migraine, COVID-19, SARS CoV-2, blood-brain barrier, anatomy, diabetes & mitochondria, pharmacology.
medical animation of We created this scientific animation to introduce stakeholders with a wide range of scientific knowledge to telomeres and their distinct spatial profiles in health and disease, and to illustrate how the Teloview diagnostic platform detects these profiles in cells. To explain how Teloview profiling works, we developed a conceptual visualization of the cellular analysis and underlying mathematical algorithms.
medical illustration of This animation laid the foundation disease awareness story for the first new migraine drug in decades: Aimovig (erenumab). It begins with the burden of disease of migraine, moves through pathophysiology, then dives into the story of a key molecular player: CGRP.  A thorough review of the migraine literature informed the script and visuals. All models and anatomy are data-driven.
medical animation of Mechanism of disease animation about hepatilin. To simplify glucose metabolism for a wide audience, we created a factory analogy in which a series of pipes & conveyor belts transport nerve signals, hormones, and nutrients between different organ “stations”. This allows viewers to see downstream effects of changing one signal. Includes: metabolic; endocrinology; type 2 diabetes; insulin; anatomy; male; scientific animation; MOD animation; disease state animation; DSE animation; schematic.
medical animation of A feature-length documentary about inherited diseases. Diverse storytelling needs called for 2 animation styles: 1) 3D visualization for immersive journeys; 2) Hand-drawn for concepts and processes. The resulting visualizations showcase incredible molecular processes for a lay audience and allow both fleeting molecular interactions and long experimental workflows to be memorably communicated. Created with Tangled Bank Studios, HHMI for PBS
medical animation of For startups & established medical device companies by top medical device animation company AXS Studio, www.axs3d.com. Created for investor presentations, premarket approval, training, instructions for use, IFU & marketing. This showreel features atrial fibrillation cardiac ablation, drug delivery device, pneumonia, pediatric cranium, 3D CT mammogram, diabetes injection pen, LVAD heart pump, diagnostic blood test, manufacturing, age-related macular degeneration, AMD, & ophthalmology.
medical animation of This medical device animation introduces cardiac surgeons and other stakeholders to the HeartWare System ventricular assist device, its use and key technological advantages. It was important to clearly illustrate the pump’s proprietary suspension system, which eliminates wear. To focus viewer attention, we rendered the system and heart photorealistically and used a simpler illustrative style for supporting elements, including operation and maintenance of the system.
medical illustration of How can a convenient hand-held device replace established, complex and costly clinical lab equipment? The answer lies in innovative design, state-of-the-art manufacturing and exceptional quality control. We created this medical device animation to clearly demonstrate the advantages of this disruptive and highly efficient solution for bedside diagnostic testing.
medical animation of Medical device animation designed to build awareness and preference for Boston Scientific’s Farapulse PFA System among electrophysiologists. Incorporates product branding with carefully planned and beautifully rendered imagery to tell the compelling story of this novel system. Data visualizations, datavis, complements messaging around the system’s workflow effectiveness. Technology, catheter, cardiology, cardiovascular, atrial fibrillation, heart anatomy, arrhythmia, cardiac surgery.
medical animation of This medical device animation about the Valeda Light Delivery System explains photobiomodulation, PMB, therapy used to treat age-related macular degeneration, or AMD. With content based upon peer-reviewed scientific literature, this mechanism of action animation presents science to address skepticism among retinal specialists. Eye, retina, photoreceptors, mitochondria, cytoplasm, cytosol, retinal cells, ophthalmology; scientific animation; beautiful; female; elderly; optometrist; optometry.
medical animation of A 3D medical animation created to educate HCPs about the MOA of a novel antibody-drug conjugate (ADC), XB002, which targets tumor cells expressing tissue factor, or TF, without disrupting normal function. Includes: mechanism of action, MOA animation, mechanism of disease, MOD animation, coagulation cascade, blood clot, rbc, red blood cells, cell membrane, lipid bilayer, oncology, cancer animation, motion graphics, mograph, biotechnology, biotech animation, pharma, datavis, pharmacology.
medical animation of We created this medical device animation to instruct clinical trial staff in the proper use of a novel drug delivery system. In a modular narrative, we describe device assembly and operation and demonstrate how its advanced technology benefits patients.
medical animation of Osteoporosis augmented reality, AR, iPad app for fragility fracture disease awareness. Clinical questions stimulate conversation with onsite medical liaisons, MSLs, and analytics provide post-congress metrics. Bone health. bone disease, disease state awareness, DSE, skeleton, booth exhibit, pharma interactive, congress, conference.
medical animation of Scientific animation about the mechanism of action, MOA, of Evenity, romosozumab, a bone forming agent that inhibits sclerostin to promote gains in bone mass by top medical animation company AXS Studio, www.axs3d.com. Bone cube, bone formation, bone resorption, bone remodeling, osteoporosis, MOA animation, scientific animation, trabecular bone, trabeculae, bone scaffold, bone matrix, cortical bone, signaling cascade, monoclonal antibody, cell migration, cell motility, pharmacology.
medical animation of We created this series of scientific animations in partnership with Fabian de Kok-Mercado at HHMI BioInteractive to explain SARS-CoV-2 biology infection, evolution and testing to a lay audience. We developed a 2D watercolour look for the 3D SARS-CoV-2 virus models using Artineering's MNPRX non-photorealistic renderer (NPR). The stylistic treatment of the characters softens the high-science content, making it more approachable for a general audience. By top medical animation company, AXS Studio
medical animation of Scientific animation about minimal residual disease, MRD, in multiple myeloma by top medical animation company AXS Studio, www.axs3d.com. Features tumor microenvironment, male, female animated characters, physician, diversity, lab technicians, scientist, cancer cell, cancer diagnosis, biotechnology animation, biotech animation, biotechnology animation, graphs, datavis, data visualization, scan, scanning, MRD animation, NGS, next-generation sequencing, mass spectrometry, flow cytometry, PET, CT.
medical animation of 2022 AMI Award of Excellence winner. MOA animation about multi-receptor tyrosine kinase, RTK, inhibitor XL092. Emphasizing the rigorous scientific evidence backing the XL092 clinical program was a top client priority. Content was consolidated into short clips, each focusing on a key message. Medical animation, mechanism of action animation, scientific animation, oncology animation, cancer animation, mograph, motion graphics, tumor micro environment, TME, angiogenesis, pharmacology.
medical illustration of Mechanism of action animation about CGRP inhibitor erenumab, Aimovig, for migraine headache by top medical animation company AXS Studio, www.axs3d.com. Includes molecular, neuroscience animation, neurology animation, brain, brainstem, blood brain barrier, synapse, neurons, CNS, PNS, monoclonal antibody, mAb & molecules. For medical education, MOA animation. Biotech animation, biotechnology animation, scientific animation, science animation; drug mechanism, pharmacology. Contact us for the video.
medical animation of Our challenge for this oncology animation was to present the proteasome as both a vital tool for healthy cells, and a key weapon of survival for cancer cells. We based the structure of our proteasome and its function on data from peer reviewed literature. A warm palette and bright lighting underscore the idea that the proteasome is not a sinister force, but rather an innocuous player in a noxious process.
medical animation of Mobile-friendly mechanism of action animation, MOA animation for patient education on social media. Concise, plain language script. Created an accessible visual identity for the molecules & cells. Bright, bold colors. 60 seconds for Instagram. Melanoma skin cancer MOA video. BRAF mutation. BRAF inhibitor. 3D scientific animation. Pfizer oncology. Molecular animation. Dermatology animation. Cancer metastasis. Pharmaceutical marketing. Biotech, biotechnology animation; pharma, pharmacology.
medical illustration of This medical animation was created for consumers to inspire wonder in the fascinating biology of the human eye and all it enables us to do. It was created in support of Bausch + Lomb's contact lens marketing campaign and featured an anatomically accurate model of the human eye and animation of light refraction through the cornea, lens and vitreous.
medical illustration of We designed this scientific illustration to explain the importance of chloride ion transport in mucous viscosity and the role played by CFTR. A dynamic layout contrasts normal  with abnormal CFTR function and explains the role of the first ever CF drug, VX-770. We based the protein models and their conformations on published molecular structure data to ensure accuracy, a key ingredient in any authentic scientific illustration, pharmacology.
Created for: Scientific American
medical animation of Concise, patient-friendly medical animation to inspire AD patients to overcome lumbar puncture hesitancy & donate CSF to Alzheimer’s Disease research. Approached from a patient perspective with a calm visual style & sensitive depiction of the main character. We consulted AD researchers to depict the procedure accurately & sensitively. Cognitive impairment, dementia, female, senior citizen, spinal cord, brain, cerebrospinal fluid, CSF, procedure, lab technician, diversity, test tube, research.
medical animation of Osteoporosis disease state education animation, DSE animation, by top medical animation company AXS Studio, www.axs3d.com. Sclerostin affects osteoblasts & osteoclasts, leading to fragility fractures. This 3D animation was paired with an interactive augmented reality, AR,  experience to provide an engaging learning experience at a conference booth. Trabecular bone, trabeculae, osteocytes, bone remodeling, bone formation, bone scaffold, scientific animation, cytokines, pharmacology.
medical animation of In the sci-fi horror feature film, Splice, Adrian Brody and Sarah Polley play scientists who defy legal and ethical boundaries, splicing human and animal DNA to create a new organism. AXS Studio created the scientific animations and illustrations for props on the film set, basing our visualizations on laboratory video footage of nuclear transfer and cell division. We leveraged our knowledge of human sectional anatomy to create the creature MRI images used on set.
medical illustration of Mechanism of disease and mechanism of action animation explores the regulation of low density lipoprotein cholesterol, LDL-C, levels in the liver. By contrasting the LDL-C processing with and without PCSK9, we demonstrate how the latter is a therapeutic target for lowering LDL-C levels in hyperlipidemia. Molecular structures & conformations based on data. pharmacology. Medical education, MOA , biotech, biotechnology, scientific animation, drug mechanism, pharmacology. Contact us for the video.
medical illustration of What better way to educate a headache specialist on the role of CGRP in migraine than to show it in their own brain! Utilizing live video tracking, we programmed MiBrain to simulate a live scan so that neuro and vascular anatomy on the screen track a user’s movements. We leverage experiential learning by showing CGRP and its receptor in structures that appear to be inside a user’s head. A photo printout puts smiles on faces and reinforces key messages.
medical animation of A web-based 3D interactive education app explaining Amgen's Bispecific T Cell Engager (BiTE) technology & the platform's ability to target different types of cancer. When users build the correct BiTE for a given tumor type, a 3D simulation runs with BiTE molecules enabling host T cells to bind & kill cancer cells. Designed for congress booth touchscreens, desktop & mobile. Biotech, biotechnology, cancer, MOA animation. https://axs3d.com/portfolio-item/seamless-hcp-engagement-anytime-anywhere/
medical animation of An immersive booth interactive at ASCO & ASH, our virtual reality, VR, microscope simulator immerses users in a battle between T cells & cancer. Learn the MOA of a new cancer immunotherapy, using a virtual histology slide with AI-driven cells. A dial allows users to zoom between micro & nano scales. Printed slide kit doubles as a handout. Includes: cancer immune therapy; leukemia; lymphoma; lung carcinoma; simulation; bispecific antibody; biotech animation; biotechnology animation; engineering.
medical animation of Guardians of the Genome is a multi-player, virtual reality (VR) science game designed to teach players about accurate DNA structure through collaborative, hands-on experiences. Equipped with special tools emulating DNA repair enzymes, players are tasked with fixing common mistakes in DNA called base-pairing errors. Experienced solo or in cooperation with friends, Guardians is a fun and immersive way to learn about this fundamental molecule of life. Supports Oculus Rift & HTC Vive controllers.
medical illustration of We created this engaging disease state education hologram to educate HCPs on certain underappreciated aspects of heart failure (HF), including cardiovascular disease (ASCVD). Participants drive the experience using touch controls, while the attractive holographic imagery doubles as a booth attract to drive traffic at a scientific affairs booth. Built-in analytics provide metrics to measure ROI.
medical illustration of A highly engaging multi-player, immuno-oncology educational game featured at ASCO, ASH and online. Playing the role of cytotoxic T cells in an evolutionary arms race with cancer cells, users interact with an AI-driven population of cancer cells that proliferate and evolve evasive mechanisms. Simple interactions and custom controllers improved accessibility for users with limited gaming experience. Built-in analytics provide metrics to measure ROI.
medical illustration of This concise animation was designed to loop on a holographic display (hologram) in a pharmaceutical congress exhibit. It functions as an educational booth attraction, alongside a full-length migraine disease awareness medical animation and interactive
medical illustration of A true first in medical communications, we created this immersive mixed reality (MR) experience to offer HCPs a new perspective on cardio-renal science and its impact on patients. Mixed reality combines live video with virtual reality (VR) to blend the real and digital worlds. We brought to life a mural of MiRA (mixed-reality avatar) for a one-on-one conversation with booth visitors at American Society of Nephrology (ASN).
medical animation of Build a Biosimilar interactive simulator gives participants an appreciation for the difficulty in making a complex biologic molecule highly similar to its reference product. Adjusting manufacturing settings, users see how small changes have significant structural & functional impacts. Participants initial their own biosimilar. Deployed to congress booths & MSL iPads simulation biotechnology animation, biotech animation, monoclonal antibody medical animation, drug development.
medical illustration of We created this medical device animation to introduce healthcare professionals to the features of the GELShield extracranial pressure relief system. We developed a soft visual style consistent with GELShield’s purpose and created renderings from 3D product models for use on the GELShield website, http://www.invictusgelshield.com/
medical animation of Here we demonstrate key technological features of Alcon's Air Optix Contact lenses that provide deposit protection and moisture retention, resulting in a more comfortable experience for wearers. Moving seamlessly between molecular and macro scales, we provide a scientifically-accurate depiction of the moisture retention technology, while maintaining a clear, clean, watery aesthetic, consistent with the brand.
medical illustration of Esquire Magazine approached us to create medical illustrations for the article “Vital Organs: Brain, Heart and Balls” by A. J. Jacobs, we put our heads and hearts into the challenge. Vetted for accuracy by medical experts Dr. David Perlmutter, Dr. Mehmet Oz, and Dr. Harry Fish, our renderings reveal what every Esquire Man should know about his vital parts.
medical animation of Dr. David Sandström and his team of top scientists at NorBAC investigate questionable advantages in biotechnology. For 3 seasons, AXS Studio created the signature CGI moments for this innovative TV drama that enabled the audience to see and think like a scientist. We called on our expertise in cell cell and molecular biology to visualize complex, and often abstract, scientific concepts described in the actors’ dialogue.
medical animation of Commissioned for outreach & education, this scientific animation details 21 days of chicken embryo development and adheres to the Australian national science curriculum: life cycles & comparative embryology. Informed by detailed research, 7 3D models were created to represent the chick at key stages of growth. This animation has been used widely in classrooms—a primary goal of the project. 14 million YouTube views as of September, 2020.

Profile

Medical animation, scientific animation, apps and experiences by Certified Medical Illustrators. You see the possibility in your science. At AXS Studio, we'll communicate it with clarity and purpose. Since 2004 we’ve been making our clients’ science and technology easy to understand and impossible to ignore. Blending expertise in biology, medicine and visual communication, we create custom animations and interactives that drive your messaging home with beautifully rendered, meticulously researched visuals.

Style/Techniques

Animation, Cartoon, Color, 3D, Apps/Mobile, Models, Microscopy, Voiceovers/Narration, VR/Virtual Reality

Subject/Specialties

Allergy / Immunology, Anatomy, Biology, Biotechnology, Cardiac Surgery / Cardiology, Cell biology / Histology, Dermatology, Disease Management, Embryology, Endocrinology / Metabolic, General Medicine, Genetics, Medical Devices, Molecular Biology, Natural Science / Nature, Neuroscience, Ophthalmology, Orthopaedics, Pediatrics, Pharmacology, Respiratory, Thoracic Surgery, Urology, Vascular Surgery, Virology, Zoology, Injuries, Oncology, Mechanism of Action (MOA), Health & Wellness, Pathology